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[瑞典接受肾脏替代治疗患者的新冠肺炎相关死亡率]

[COVID-19 related mortality in Swedish patients with renal replacement therapy].

作者信息

Segelmark Mårten, Segelmark Leo, Smolander Jessica, Rydell Helena, Evans Marie, Stendahl Maria

机构信息

professor, överläkare, institutionen för kliniska vetenskaper i Lund, Lunds universitet; VO njurmedicin och reumatologi, Skånes universitetssjukhus.

läkare, forskningsassistent, Svenskt njurregister.

出版信息

Lakartidningen. 2021 Nov 16;118:21051.

PMID:35502607
Abstract

Data from the Swedish Renal Registry (SRR) show that during the period March 16, 2020 to March 15, 2021 0.4% of all renal transplant recipients and 3% of all dialysis patients died due to COVID-19 in Sweden. Of all registered deaths, 20% were attributed to COVID-19.  In the age group 50-59 years the risk ratio for COVID-19 related mortality was 16 (95% CI 6.5-38) among transplant recipients and 22 (95% CI 7.1-69) among dialysis patients, compared to the background population in the same age group. Excess mortality, compared to the five years preceding the pandemic, was 30% for transplant recipients and 8.7% for dialysis patients, compared to 7.7% for the entire Swedish population. Detailed reports were sent to SRR for 864 patients with confirmed COVID-19 infection representing 5.0% of all transplant recipients and 13% of all dialysis patients. The case fatality rate was 7.0% and 21% respectively.

摘要

瑞典肾脏登记处(SRR)的数据显示,在2020年3月16日至2021年3月15日期间,瑞典所有肾移植受者中有0.4%以及所有透析患者中有3%死于新冠病毒病(COVID-19)。在所有登记的死亡病例中,20%归因于COVID-19。在50-59岁年龄组中,与同年龄组的背景人群相比,肾移植受者中COVID-19相关死亡率的风险比为16(95%置信区间6.5-38),透析患者中为22(95%置信区间7.1-69)。与大流行前的五年相比,肾移植受者的超额死亡率为30%,透析患者为8.7%,而瑞典全体人口为7.7%。代表所有肾移植受者5.0%和所有透析患者13%的864例确诊COVID-19感染患者的详细报告已发送至SRR。病死率分别为7.0%和21%。

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引用本文的文献

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Results of the first nationwide cohort study of outcomes in dialysis and kidney transplant patients before and after vaccination for COVID-19.首个全国性队列研究结果:COVID-19 疫苗接种前后透析和肾移植患者的结局。
Nephrol Dial Transplant. 2023 Oct 31;38(11):2607-2616. doi: 10.1093/ndt/gfad151.
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A third dose SARS‑CoV‑2 BNT162b2 mRNA vaccine results in improved immune response in hemodialysis patients.第三剂 SARS-CoV-2 BNT162b2 mRNA 疫苗可提高血液透析患者的免疫应答。
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