Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Division of Ophthalmology, Goldschleger Eye Institute, Sheba Medical Center, Sheba Talpiot Medical Leadership Program, Tel Hashomer, Israel.
Ophthalmic Plast Reconstr Surg. 2022;38(5):490-495. doi: 10.1097/IOP.0000000000002182. Epub 2022 May 3.
To determine the risk factors impacting the surgical success of primary monocanalicular stent intubation for congenital nasolacrimal duct obstruction (CNLDO).
This is a retrospective interventional case series of patients 18 years and younger treated more than a 12-year period with monocanalicular stent intubation with inferior turbinate fracture for CNLDO by a single surgeon. Patients with dacryocystoceles, dacryocystitis, Down syndrome and previous tear duct surgery were excluded. An intraoperative grading scale of tear duct stenosis, date of stent removal, stent length, and postoperative symptoms were recorded. Surgical success was defined as the complete resolution of symptoms.
One thousand four hundred sixty-nine stents were placed in 1,001 pediatric participants (533 unilateral, 468 bilateral). The mean age at surgery was 1.86 years (0.1-18.07). The mean follow up was 34.99 months (0.43-134.3) with mean in-office stent removal at 3.41 months (0.63-36.9). Early stent loss occurred in 14.8% intubations (217/1,469). The overall success rate was 92.4% (1,357/1,469 eyes). Subjects less than the age of 4 years had a success rate of 92.8% (1,296/1,397) compared with 84.7% (61/72) in children more than 4. In multivariable analysis, bilateral surgery, severe tear duct stenosis, and early stent loss were significantly associated with higher risk of surgical failure.
Severe tear duct stenosis, early stent loss, and bilateral surgery were significant risk factors for surgical failure. While the success rate stratified by age at surgery suggested a lower success after the age of 4. Primary monocanalicular stent intubation is an effective and safe treatment for CNLDO sparing a child the need for multiple staged surgeries.
确定影响先天性鼻泪管阻塞(CNLDO)初次单鼻内管支架插管手术成功率的危险因素。
这是一项回顾性介入病例系列研究,纳入了在 12 年以上时间内由同一位外科医生采用下鼻甲骨折行单鼻内管支架插管治疗的 18 岁及以下患者。排除有泪囊膨出、泪囊炎、唐氏综合征和既往泪道手术的患者。记录术中泪道狭窄分级、支架取出日期、支架长度和术后症状。手术成功定义为症状完全缓解。
在 1001 例儿科患者(533 例单侧,468 例双侧)中放置了 1469 个支架。手术时的平均年龄为 1.86 岁(0.1-18.07)。平均随访 34.99 个月(0.43-134.3),平均门诊支架取出时间为 3.41 个月(0.63-36.9)。14.8%(217/1469)的插管出现早期支架丢失。总体成功率为 92.4%(1357/1469 眼)。年龄小于 4 岁的患者成功率为 92.8%(1296/1397),而年龄大于 4 岁的患者成功率为 84.7%(61/72)。多变量分析显示,双侧手术、重度泪道狭窄和早期支架丢失与手术失败风险增加显著相关。
重度泪道狭窄、早期支架丢失和双侧手术是手术失败的显著危险因素。虽然按手术年龄分层的成功率提示 4 岁后成功率较低,但初次单鼻内管支架插管是一种有效且安全的 CNLDO 治疗方法,可以避免儿童需要多次分期手术。