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COVID-19大流行期间造血干细胞移植患者的COVID-19恐惧及生活质量评估

Evaluation of COVID-19 fear and quality of life in patients with haematopoietic stem cell transplantation during the COVID-19 pandemic.

作者信息

Çelik Serhat, Güven Zeynep Tuğba, İpekten Funda, Keklik Muzaffer, Ünal Ali, Kaynar Leylagül

机构信息

Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

Department of Biostatistics, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

出版信息

Eur J Cancer Care (Engl). 2022 Sep;31(5):e13604. doi: 10.1111/ecc.13604. Epub 2022 May 3.

Abstract

OBJECTIVE

We aimed to determine the coronavirus disease 2019 (COVID-19) fear state in haematopoietic stem cell transplant patients and to examine its relationship with quality of life.

METHODS

In this prospective study, 64 patients who underwent HSCT during the pandemic were included. The COVID-19 fear situation was evaluated with the Fear of COVID-19 Scale (FCV-19S). Quality of life was evaluated with the European Organisation for Quality of Life Research and Treatment Core Questionnaire (EORTC QLQ-C30) (Version 3).

RESULTS

The median FCV-19S score was 16.5 (12.0-22.0). The FCV-19S score was significantly higher in urban residents than rural residents. The general health score was 59.64 ± 20.04. The strongest positive correlation between fear level and life quality was found in emotional function. A weak, significant, positive correlation was observed between role function, nausea-vomiting, pain, appetite loss and fear level.

CONCLUSION

FCV-19S is a quick, safe and valid tool that can be used to determine the COVID-19 fear level in vulnerable patient groups such as HSCT patients and to direct them to the necessary psycho-oncological support.

摘要

目的

我们旨在确定造血干细胞移植患者对2019冠状病毒病(COVID-19)的恐惧状态,并研究其与生活质量的关系。

方法

在这项前瞻性研究中,纳入了64名在疫情期间接受造血干细胞移植的患者。采用COVID-19恐惧量表(FCV-19S)评估对COVID-19的恐惧情况。使用欧洲生活质量研究与治疗组织核心问卷(EORTC QLQ-C30)(第3版)评估生活质量。

结果

FCV-19S评分中位数为16.5(12.0 - 22.0)。城市居民的FCV-19S评分显著高于农村居民。总体健康评分为59.64±20.04。在情感功能方面,恐惧水平与生活质量之间存在最强的正相关。在角色功能、恶心呕吐、疼痛、食欲减退与恐惧水平之间观察到微弱但显著的正相关。

结论

FCV-19S是一种快速、安全且有效的工具,可用于确定造血干细胞移植患者等脆弱患者群体对COVID-19的恐惧水平,并指导他们获得必要的心理肿瘤学支持。

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