Proto C, Quadri A, Ratti S, Levi G F, Prandini B D
G Ital Cardiol. 1978;8(7):743-51.
A double blind cross-over trial has been carried out on the effects of a nicotinic acid compound on 27 patients affected by hyperlipidemia. The subjects have been treated over one year according the following plan: two peroids of 90 days each with the drug and two with placebo. The statistical analysis showed a significant reduction of serum cholesterol triglycerides, phospholipids and total lipids. In 4 patients out of 27, the treatment has not been completed because of drug intollerance.
针对一种烟酸化合物对27名高脂血症患者的影响进行了一项双盲交叉试验。受试者按照以下方案接受了一年的治疗：两个为期90天的用药期和两个使用安慰剂的时期。统计分析显示血清胆固醇、甘油三酯、磷脂和总脂质显著降低。27名患者中有4名因药物不耐受而未完成治疗。
