评估系统性红斑狼疮患者左心室收缩同步性的峰值应变离散度。
Assessment of left ventricular systolic synchrony by peak strain dispersion in patients with systemic lupus erythematosus.
机构信息
Department of Ultrasound, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, P.R. China.
出版信息
Eur Rev Med Pharmacol Sci. 2022 Apr;26(8):2840-2846. doi: 10.26355/eurrev_202204_28614.
OBJECTIVE
The aim of the study was to investigate the clinical value of the peak strain dispersion (PSD) in evaluating left ventricular (LV) systolic synchrony in patients with systemic lupus erythematosus (SLE).
PATIENTS AND METHODS
58 SLE patients without cardiovascular diseases and 60 healthy subjects were enrolled in the study. Both groups were examined by transthoracic two-dimensional echocardiography. Traditional parameters were measured by conventional echocardiography. Two-dimensional speckle tracking imaging (2D-STI) was used to analyze the PSD and LV global longitudinal strain (LVGLS). Related ultrasound and blood test results were analyzed and compared.
RESULTS
The PSD was significantly higher in SLE patients than in controls (p<0.05). The LVGLS was significantly lower in SLE patients than in controls (p<0.05). The PSD was negatively correlated with the LVGLS.
CONCLUSIONS
LV systolic synchrony is impaired in patients with SLE disease. The PSD can be used as a new reliable index to evaluate LV systolic synchrony.
目的
本研究旨在探讨峰值应变离散度（PSD）在评估系统性红斑狼疮（SLE）患者左心室（LV）收缩同步性中的临床价值。
患者与方法
本研究纳入了 58 例无心血管疾病的 SLE 患者和 60 名健康对照者。两组均接受经胸二维超声心动图检查。常规超声心动图测量传统参数。二维斑点追踪成像（2D-STI）用于分析 PSD 和 LV 整体纵向应变（LVGLS）。分析并比较相关的超声和血液检查结果。
结果
SLE 患者的 PSD 明显高于对照组（p<0.05）。SLE 患者的 LVGLS 明显低于对照组（p<0.05）。PSD 与 LVGLS 呈负相关。
结论
SLE 患者的 LV 收缩同步性受损。PSD 可作为评估 LV 收缩同步性的一种新的可靠指标。
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