Thoracic Oncology Unit, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center (CTIC), Bogotá, Colombia.
Am Soc Clin Oncol Educ Book. 2022 Apr;42:1-7. doi: 10.1200/EDBK_349951.
Lung cancer represents a considerable global health threat, leading the list in terms of cancer-related deaths worldwide. An important proportion of lung cancer cases occur within Latin America, and current projections show that over the next decade, the number of deaths due to lung cancer will double in the region, underscoring the need to implement evidence-based interventions to improve outcomes. Several challenges have limited the progress in lung cancer research in Latin America for many years, though recently the surge of multidisciplinary, transnational, and transcultural research groups have overcome many of these limitations. The increase in region-specific knowledge has improved cancer care in the area, providing clinicians with a specific demographic and molecular profile for Hispanic patients with lung cancer; as a result, the implementation of precision oncology has benefited from a profound knowledge of the patient profile. Nonetheless, there are still challenges to improve research in Latin America, including stabilizing funding sources to continue independent research, supporting mentoring programs and an early immersion in clinical research for early career fellows, and overcoming barriers for publishing.
肺癌是全球健康的重大威胁,在全球癌症相关死亡病例中位居前列。拉丁美洲有相当一部分肺癌病例,目前的预测显示,在未来十年内,该地区因肺癌导致的死亡人数将翻一番,这凸显了需要实施基于证据的干预措施来改善预后。多年来,一些挑战限制了拉丁美洲肺癌研究的进展,但最近多学科、跨国界和跨文化研究小组的涌现克服了其中的许多限制。特定于该地区的知识的增加改善了该地区的癌症治疗,为临床医生提供了肺癌西班牙裔患者的特定人口统计学和分子特征;因此,精准肿瘤学的实施得益于对患者特征的深入了解。尽管如此,仍需要克服一些挑战来改善拉丁美洲的研究,包括稳定资金来源以继续独立研究,为早期职业研究员提供指导计划和早期临床研究方面的支持,以及克服出版方面的障碍。