First Affiliated Hospital of Jinan University, Guangzhou, China; Department of Medical Ultrasound, Gaozhou People's Hospital, Gaozhou, Guangdong, China.
First Affiliated Hospital of Jinan University, Guangzhou, China; Department of Medical Ultrasound, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Ultrasound Med Biol. 2022 Aug;48(8):1420-1428. doi: 10.1016/j.ultrasmedbio.2022.03.005. Epub 2022 Apr 30.
The goal of the work described here was to compare high-frequency contrast-enhanced ultrasound (HF-CEUS) and conventional high-frequency ultrasound (HFU) with respect to performance and safety during ultrasound-guided biopsy of pleural lesions. We performed a retrospective study on patients with pleural lesions who received the puncture biopsy under the guidance of conventional HFU or HF-CEUS between August 2018 and August 2021. These patients received either a conventional HF-U (HF-U group) or HF-CEUS (HF-CEUS group) examination. Clinical characteristics, pathological results, ultrasonic images and complications were compared between these two groups. A total of 144 patients were enrolled, with 70 in the HFU group and 74 in the HF-ECUS group. Except for the time required for ultrasonic localization (p < 0.05), there were no significant differences in clinical characteristics between the two groups. The success rate of biopsy in the HF-CEUS group was higher than that in the HFU group (93.2% vs. 81.4%, p < 0.05). There were significant differences between the two groups in terms of measurements of pleural thickness, necrotic areas, large blood vessels and lesion boundaries (p < 0.05). The complication rates were 2.7% and 12.9% in the HF-CEUS and HFU groups, respectively, with a significant difference (p < 0.05). Compared with conventional HFU, the HF-CEUS-guided pleural biopsy had a better success rate and fewer complications. HF-CEUS could facilitate the biopsy in patients with pleural lesions.
本研究旨在比较高频超声造影（HF-CEUS）与高频超声（HFU）引导下经皮胸膜活检的效能和安全性。回顾性分析 2018 年 8 月至 2021 年 8 月我院收治的 144 例行超声引导下胸膜活检的患者资料，根据引导方法的不同分为 HFU 组（70 例）和 HF-CEUS 组（74 例）。对比两组患者的临床资料、超声图像特征、病理结果及并发症发生情况。除了超声定位时间（p < 0.05）外，两组患者的一般资料差异无统计学意义。HF-CEUS 组的活检成功率明显高于 HFU 组（93.2% vs. 81.4%，p < 0.05）。HF-CEUS 组的胸膜厚度、坏死区、大血管和病灶边界的超声测量值均明显优于 HFU 组（p < 0.05）。HF-CEUS 组和 HFU 组的并发症发生率分别为 2.7%和 12.9%，差异有统计学意义（p < 0.05）。与高频超声相比，HF-CEUS 引导下胸膜活检具有更高的成功率和更少的并发症。HF-CEUS 可提高胸膜病变患者的活检成功率，减少并发症的发生。
