Flaschka G, Desoye G
Neurochirurgia (Stuttg). 1987 Jan;30(1):5-7. doi: 10.1055/s-2008-1053645.
210 patients harbouring an intracranial tumour were tested for CEA plasma levels. It could be shown that this investigation was neither a useful screening test for detecting brain neoplasms nor suitable for follow-up on operated brain tumours. However, with the CEA plasma investigation an additional preoperative test is available for distinguishing between primary and secondary brain tumours. The positive evidence is only 29%, but in case of a CEA plasma value above 5.0 ng/ml a metastasis is indicated with a probability of 91%.
对210例颅内肿瘤患者进行了癌胚抗原(CEA)血浆水平检测。结果表明,该检测既不是检测脑肿瘤的有效筛查试验,也不适用于脑肿瘤手术后的随访。然而,通过CEA血浆检测,可获得一项额外的术前检测,用于区分原发性和继发性脑肿瘤。阳性证据仅为29%,但如果CEA血浆值高于5.0 ng/ml,则提示转移的概率为91%。