Chapuis P H, Newland R C, Payne J E, Macpherson J G, Pheils M T
Med J Aust. 1980 Aug 9;2(3):140-3.
Carcinoembryonic antigen (CEA) levels were estimated in 117 patients before resection of colorectal cancer. Twenty-six per cent of patients had normal CEA values. CEA values rose progressively with tumour stages, and were higher in patients with liver metastases compared with patients with only lymph-node spread. No significant difference in survival, independent of stage of spread, was found between patients with preoperative levels of antigen greater or less than 5 ng/mL of plasma. Similarly, there was no significant difference between the survival of patients with stage B or stage C tumours regardless of whether their levels of the antigen were greater or less than 10 ng/mL of plasma. A single preoperative CEA estimation does not add to the prognostic information available from careful assessment of the stage of tumour spread.
对117例结直肠癌患者在手术切除前进行了癌胚抗原（CEA）水平评估。26%的患者CEA值正常。CEA值随肿瘤分期逐渐升高，与仅有淋巴结转移的患者相比，肝转移患者的CEA值更高。术前抗原水平高于或低于5 ng/mL血浆的患者，无论转移分期如何，生存率均无显著差异。同样，B期或C期肿瘤患者，无论其抗原水平高于或低于10 ng/mL血浆，生存率也无显著差异。术前单次CEA评估并不能增加通过仔细评估肿瘤转移分期所获得的预后信息。
