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利用 HRV 特征和机器学习提高时间分辨率检测心律失常的效果。

Effect of temporal resolution on the detection of cardiac arrhythmias using HRV features and machine learning.

机构信息

Biomedical Engineering Faculty, Technion-IIT, Haifa, Israel.

出版信息

Physiol Meas. 2022 Apr 28;43(4). doi: 10.1088/1361-6579/ac6561.

DOI:10.1088/1361-6579/ac6561
PMID:35506573
Abstract

Arrhythmia is an abnormal cardiac rhythm that affects the pattern and rate of the heartbeat. Wearable devices with the functionality to measure and store heart rate (HR) data are growing in popularity and enable diagnosing and monitoring arrhythmia on a large scale. The typical sampling resolution of HR data available from non-medical grade wearable devices varies from seconds to several minutes depending on the device and its settings. However, the impact of sampling resolution on the performance and quality of arrhythmia detection has not yet been quantified.In this study, we investigated the detection and classification of three arrhythmias, namely atrial fibrillation, bradycardia, tachycardia, from down-sampled HR data with various temporal resolution (5-, 15-, 30- and 60 s averages) in 1 h segments extracted from an annotated Holter ECG database acquired at the University of Virginia Heart Station. For the classification task, a total of 15 common heart rate variability (HRV) features were engineered based on the HR time series of each patient. Three different types of machine learning classifiers were evaluated, namely logistic regression, support vector machine and random forest.A decrease in temporal resolution drastically impacted the detection of atrial fibrillation but did not substantially affect the detection of bradycardia and tachycardia. A HR resolution up to 15 s average demonstrated reasonable performance with a sensitivity of 0.92 and a specificity of 0.86 for a multiclass random forest classifier.HRV features extracted from low resolution long HR recordings have the potential to increase the early detection of arrhythmias in undiagnosed individuals.

摘要

心律失常是一种影响心跳节律和频率的异常心脏节律。具有测量和存储心率 (HR) 数据功能的可穿戴设备越来越受欢迎,能够大规模诊断和监测心律失常。非医疗级可穿戴设备提供的 HR 数据的典型采样分辨率根据设备及其设置,从几秒到几分钟不等。然而,采样分辨率对心律失常检测的性能和质量的影响尚未量化。在这项研究中,我们研究了从弗吉尼亚大学心脏站采集的标注 Holter ECG 数据库中 1 小时片段中以各种时间分辨率(5、15、30 和 60 秒平均值)下采样的 HR 数据中三种心律失常(心房颤动、心动过缓、心动过速)的检测和分类。对于分类任务,总共基于每位患者的 HR 时间序列设计了 15 个常见心率变异性 (HRV) 特征。评估了三种不同类型的机器学习分类器,即逻辑回归、支持向量机和随机森林。时间分辨率的降低极大地影响了心房颤动的检测,但对心动过缓和心动过速的检测没有实质性影响。HR 分辨率高达 15 秒平均值,对于多类随机森林分类器,具有合理的性能,敏感性为 0.92,特异性为 0.86。从低分辨率的长 HR 记录中提取的 HRV 特征有可能增加对未诊断个体心律失常的早期检测。

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