Warren K S
Gut. 1978 Jun;19(6):572-7. doi: 10.1136/gut.19.6.572.
Schistosomiasis mansoni and japonica, helminth infections involving the livers of 100 million people, are among the 'great neglected diseases of mankind' on the basis both of their prevalence and the relative lack of interest shown in them by clinicians and biomedical investigators. Schistosomiasis is not only an interesting disease in itself but has the added advantage of providing unique human and animal models of hepatic pathophysiology, immunopathogenesis, and collagen metabolism.
曼氏血吸虫病和日本血吸虫病是两种累及一亿人肝脏的蠕虫感染病,鉴于其流行程度以及临床医生和生物医学研究人员对它们相对缺乏关注,它们属于“人类重大被忽视疾病”。血吸虫病本身不仅是一种有趣的疾病,而且还有额外的优势,即能提供肝脏病理生理学、免疫发病机制和胶原代谢方面独特的人类和动物模型。