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肝脾血吸虫病:一种严重被忽视的肝脏疾病。

Hepatosplenic schistosomiasis: a great neglected disease of the liver.

作者信息

Warren K S

出版信息

Gut. 1978 Jun;19(6):572-7. doi: 10.1136/gut.19.6.572.

Abstract

Schistosomiasis mansoni and japonica, helminth infections involving the livers of 100 million people, are among the 'great neglected diseases of mankind' on the basis both of their prevalence and the relative lack of interest shown in them by clinicians and biomedical investigators. Schistosomiasis is not only an interesting disease in itself but has the added advantage of providing unique human and animal models of hepatic pathophysiology, immunopathogenesis, and collagen metabolism.

摘要

曼氏血吸虫病和日本血吸虫病是两种累及一亿人肝脏的蠕虫感染病,鉴于其流行程度以及临床医生和生物医学研究人员对它们相对缺乏关注,它们属于“人类重大被忽视疾病”。血吸虫病本身不仅是一种有趣的疾病,而且还有额外的优势,即能提供肝脏病理生理学、免疫发病机制和胶原代谢方面独特的人类和动物模型。

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本文引用的文献

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BLOOD AMMONIA DURING BLEEDING FROM ESOPHAGEAL VARICES IN PATIENTS WITH HEPATOSPLENIC SCHISTOSOMIASIS.
N Engl J Med. 1964 Oct 29;271:921-6. doi: 10.1056/NEJM196410292711802.

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