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雄激素剥夺治疗22年后寡转移前列腺腺癌的睾丸复发

Testicular recurrence of oligometastatic prostatic adenocarcinoma after 22 years of androgen deprivation therapy.

作者信息

Fortier Alexa, Mokadem Seif, Cornet Emlyn, Cornu Jean-Nicolas, Sabourin Jean-Christophe, Pfister Christian

机构信息

Urology Department, Rouen University Hospital, 1 Rue de Germont, 76031, Rouen Cedex, France.

Department of Anatomopathology, Rouen University Hospital, 1 Rue de Germont, 76031, Rouen Cedex, France.

出版信息

Urol Case Rep. 2022 Mar 17;43:102055. doi: 10.1016/j.eucr.2022.102055. eCollection 2022 Jul.

DOI:10.1016/j.eucr.2022.102055
PMID:35509726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9058943/
Abstract

Testicular metastasis of carcinoma is a rare condition. We report a rare case of right testicular metastasis of prostatic adenocarcinoma in an 84 years old patient, after more than 20 years of controlled disease under androgen deprivation therapy. Follow-up consisted in PSA monitoring, clinical examination, CT and bone scan. Biological recurrence, right testicular mass and finally right total orchiectomy allowed the diagnosis of a right testicular metastasis. PSA monitoring and clinical surveillance are important tools for diagnosing metastatic localisations.

摘要

癌的睾丸转移是一种罕见情况。我们报告一例84岁患者发生前列腺腺癌右睾丸转移的罕见病例，该患者在雄激素剥夺治疗下疾病得到控制超过20年。随访包括前列腺特异性抗原（PSA）监测、临床检查、CT和骨扫描。生物学复发、右侧睾丸肿物，最终右侧睾丸全切术确诊为右侧睾丸转移。PSA监测和临床监测是诊断转移部位的重要工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/b8ff12917590/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/b22b5ae430ce/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/02b096185057/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/b8ff12917590/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/b22b5ae430ce/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/02b096185057/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53aa/9058943/b8ff12917590/gr3.jpg

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Pathologica. 2024 Feb;116(1):69-74. doi: 10.32074/1591-951X-940.
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本文引用的文献

1
Oligometastasis to testis in prostate cancer: Role of gallium-68 prostate-specific membrane antigen positron-emission tomography computed tomography.前列腺癌睾丸寡转移：镓-68前列腺特异性膜抗原正电子发射断层扫描计算机断层扫描的作用
World J Nucl Med. 2020 Aug 22;20(1):113-116. doi: 10.4103/wjnm.WJNM_39_20. eCollection 2021 Jan-Mar.
2
Isolated testicular prostate cancer metastasis.孤立性睾丸前列腺癌转移
Scand J Urol. 2017 Oct;51(5):426-427. doi: 10.1080/21681805.2017.1347818. Epub 2017 Jul 26.
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Testicular metastases: a poor prognostic factor in patients with advanced prostate cancer.
World J Urol. 2009 Feb;27(1):113-5. doi: 10.1007/s00345-008-0322-8. Epub 2008 Sep 2.
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Testicular metastasis as isolated recurrence after radical prostatectomy. A first case.睾丸转移作为前列腺癌根治术后孤立性复发的首例病例
Int J Impot Res. 2007 Jan-Feb;19(1):108-9. doi: 10.1038/sj.ijir.3901460. Epub 2006 Mar 23.
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Secondary testicular tumors.继发性睾丸肿瘤。
Cancer. 1972 Aug;30(2):481-5. doi: 10.1002/1097-0142(197208)30:2<481::aid-cncr2820300228>3.0.co;2-x.