• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A next-generation vaccine for broader and long-lasting COVID-19 protection.

作者信息

Xi Jinxiang, Si Xiuhua April

机构信息

Department of Biomedical Engineering University of Massachusetts Lowell Massachusetts USA.

Department of Aerospace Industrial, and Mechanical Engineering California Baptist University Riverside California USA.

出版信息

MedComm (2020). 2022 May 2;3(2):e138. doi: 10.1002/mco2.138. eCollection 2022 Jun.

DOI:10.1002/mco2.138
PMID:35509871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9059810/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/9059810/bf2aa7fc5fe3/MCO2-3-e138-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/9059810/bf2aa7fc5fe3/MCO2-3-e138-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/9059810/bf2aa7fc5fe3/MCO2-3-e138-g001.jpg

相似文献

1
A next-generation vaccine for broader and long-lasting COVID-19 protection.一种用于提供更广泛、持久的新冠病毒防护的下一代疫苗。
MedComm (2020). 2022 May 2;3(2):e138. doi: 10.1002/mco2.138. eCollection 2022 Jun.
2
Impact of systemic or mucosal immunity to adenovirus on Ad-based Ebola virus vaccine efficacy in guinea pigs.腺病毒的全身或黏膜免疫对基于腺病毒的埃博拉病毒疫苗在豚鼠中的疗效的影响。
J Infect Dis. 2011 Nov;204 Suppl 3:S1032-42. doi: 10.1093/infdis/jir332.
3
Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans.气溶胶传递而非肌肉注射腺病毒载体结核疫苗可诱导人体呼吸道黏膜免疫。
JCI Insight. 2022 Feb 8;7(3):e155655. doi: 10.1172/jci.insight.155655.
4
Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis.用腺病毒载体疫苗进行鼻内加强免疫可显著增强经肠胃外注射卡介苗对肺结核的免疫保护作用。
Infect Immun. 2006 Aug;74(8):4634-43. doi: 10.1128/IAI.00517-06.
5
Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization.重组病毒载体结核病疫苗用于呼吸道黏膜免疫
Tuberculosis (Edinb). 2006 May-Jul;86(3-4):211-7. doi: 10.1016/j.tube.2006.01.017. Epub 2006 Feb 28.
6
Corrigendum: Differential biodistribution of adenoviral-vectored vaccine following intranasal and endotracheal deliveries leads to different immune outcomes.勘误:鼻内和气管内接种腺病毒载体疫苗后的生物分布差异导致不同的免疫结果。
Front Immunol. 2023 Feb 7;14:1151809. doi: 10.3389/fimmu.2023.1151809. eCollection 2023.
7
Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice.用于诱导持久体液免疫介导的对小鼠流感广泛保护的鼻内腺病毒载体疫苗。
J Virol. 2014 Sep 1;88(17):9693-703. doi: 10.1128/JVI.00823-14. Epub 2014 Jun 11.
8
A single intranasal administration of virus-like particle vaccine induces an efficient protection for mice against human respiratory syncytial virus.单次鼻腔内给予病毒样颗粒疫苗可有效保护小鼠免受人类呼吸道合胞病毒感染。
Antiviral Res. 2017 Aug;144:57-69. doi: 10.1016/j.antiviral.2017.05.005. Epub 2017 May 18.
9
Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis.用基于重组腺病毒的疫苗进行单次黏膜免疫而非肠胃外免疫,可提供针对肺结核的有效保护。
J Immunol. 2004 Nov 15;173(10):6357-65. doi: 10.4049/jimmunol.173.10.6357.
10
Intranasal mucosal boosting with an adenovirus-vectored vaccine markedly enhances the protection of BCG-primed guinea pigs against pulmonary tuberculosis.用腺病毒载体疫苗进行鼻内粘膜加强免疫可显著增强卡介苗初免豚鼠对肺结核的保护作用。
PLoS One. 2009 Jun 10;4(6):e5856. doi: 10.1371/journal.pone.0005856.

引用本文的文献

1
Assessing Nasal Epithelial Dynamics: Impact of the Natural Nasal Cycle on Intranasal Spray Deposition.评估鼻上皮动力学:自然鼻周期对鼻内喷雾沉积的影响。
Pharmaceuticals (Basel). 2024 Jan 6;17(1):73. doi: 10.3390/ph17010073.
2
Optimized gravity-driven intranasal drop administration delivers significant doses to the ostiomeatal complex and maxillary sinus.优化的重力驱动鼻内滴剂给药可将显著剂量递送至鼻旁窦口复合体和上颌窦。
Drug Deliv Transl Res. 2024 Jul;14(7):1839-1859. doi: 10.1007/s13346-023-01488-4. Epub 2023 Dec 4.
3
Delivery of Agarose-aided Sprays to the Posterior Nose for Mucosa Immunization and Short-term Protection against Infectious Respiratory Diseases.

本文引用的文献

1
Development and Challenges of Nasal Spray Vaccines for Short-term COVID-19 Protection.用于短期新冠病毒防护的鼻喷疫苗的研发与挑战
Curr Pharm Biotechnol. 2022;23(14):1671-1677. doi: 10.2174/1389201023666220307092527.
2
SARS-CoV-2 is associated with changes in brain structure in UK Biobank.在英国生物银行中,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)与大脑结构变化有关。
Nature. 2022 Apr;604(7907):697-707. doi: 10.1038/s41586-022-04569-5. Epub 2022 Mar 7.
3
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2.
琼脂喷雾递送至鼻腔后部进行黏膜免疫并短期预防传染性呼吸道疾病。
Curr Pharm Biotechnol. 2024;25(6):787-798. doi: 10.2174/1389201024666230801142913.
4
A Supine Position and Dual-Dose Applications Enhance Spray Dosing to the Posterior Nose: Paving the Way for Mucosal Immunization.仰卧位和双剂量应用可增强鼻后部喷雾给药:为黏膜免疫铺平道路。
Pharmaceutics. 2023 Jan 20;15(2):359. doi: 10.3390/pharmaceutics15020359.
呼吸道黏膜递呈的新一代 COVID-19 疫苗可对 SARS-CoV-2 的原始株和变异株提供强大保护。
Cell. 2022 Mar 3;185(5):896-915.e19. doi: 10.1016/j.cell.2022.02.005. Epub 2022 Feb 9.
4
Nasally inhaled therapeutics and vaccination for COVID-19: Developments and challenges.用于新型冠状病毒肺炎的鼻腔吸入疗法和疫苗接种:进展与挑战
MedComm (2020). 2021 Dec 14;2(4):569-586. doi: 10.1002/mco2.101. eCollection 2021 Dec.
5
SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation.SARS-CoV-2 刺突与 ACE2 的结合使 S2' 位点裂解和融合起始。
Proc Natl Acad Sci U S A. 2022 Jan 4;119(1). doi: 10.1073/pnas.2111199119.
6
Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic.SARS-CoV-2大流行中的腺病毒载体疫苗平台。
NPJ Vaccines. 2021 Aug 5;6(1):97. doi: 10.1038/s41541-021-00356-x.
7
Unbiased Screens Show CD8 T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein.非偏向性筛选表明 COVID-19 患者的 CD8 T 细胞识别 SARS-CoV-2 中的共享表位,这些表位主要位于 Spike 蛋白之外。
Immunity. 2020 Nov 17;53(5):1095-1107.e3. doi: 10.1016/j.immuni.2020.10.006. Epub 2020 Oct 20.
8
SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection.SARS-CoV-2 T 细胞免疫:特异性、功能、持久性及其在保护中的作用。
Sci Immunol. 2020 Jul 17;5(49). doi: 10.1126/sciimmunol.abd6160.
9
SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an perspective.靶向 SARS-CoV-2 RNA 依赖性 RNA 聚合酶(RdRp):一个研究视角。
J Biomol Struct Dyn. 2021 Jun;39(9):3204-3212. doi: 10.1080/07391102.2020.1761882. Epub 2020 May 6.
10
Processing ribonucleotides incorporated during eukaryotic DNA replication.处理真核生物DNA复制过程中掺入的核糖核苷酸。
Nat Rev Mol Cell Biol. 2016 Jun;17(6):350-63. doi: 10.1038/nrm.2016.37. Epub 2016 Apr 20.