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塞尔维亚共和国现役军人中冠状动脉疾病传统心血管危险因素及纤维蛋白原升高的患病率:一项横断面研究。

Prevalence of traditional cardiovascular risk factors for coronary artery disease and elevated fibrinogen among active military personnel in Republic of Serbia: A cross-sectional study.

作者信息

Pandrc Milena, Ratković Nenad, Perić Vitomir, Stojanović Maja, Kostovski Vanja, Rančić Nemanja

机构信息

Military Medical Academy, Clinic for Urgent Internal Medicine, Belgrade.

Military Medical Academy, Sector for treatment, Belgrade.

出版信息

J Med Biochem. 2022 Apr 8;41(2):221-229. doi: 10.5937/jomb0-33428.

Abstract

BACKGROUND

It is well known that less than 1% of the population achieves ideal cardiovascular health, and 65% of patients do not have their conventional risk biomarkers under control. Military service has its own particularities that may contribute to cardiovascular risk.

METHODS

To define the preventive strategy goals, we analysed the prevalence of traditional cardiovascular risk factors for coronary artery disease and elevated fibrinogen among active military personnel in the Republic of Serbia.

RESULTS

The cross-sectional study included 738 individuals older than 20 years, mostly between 31 and 40 years old. The mean value of SBP for the whole group was 122.39± 9.42 mmHg, and for the DBP, it was 79.94±6.56 mmHg. Among active military personnel, 72.7% (533) had prehypertension, and 13.8% (101) was hypertensive. Both body mass and BMI index among the observed age subgroups were found to increase with the age of the patients and cholesterol values. HDL cholesterol values also differed statistically significantly between age subgroups, with the proportion of individuals with HDL less than 1.5 mmol/L in all subgroups being about 85%, the only in the 41-50 age group was lower, 76.4%. LDL cholesterol and the proportion of individuals who had LDL 3.5 increases with the age of patients, and an identical trend was recorded with triglycerides. With ageing, fibrinogen levels increased.

CONCLUSIONS

Those findings considering cardio and cerebrovascular risk factors would help create a new approach for primary prevention for these categories of individuals.

摘要

背景

众所周知,不到1%的人口拥有理想的心血管健康状况,65%的患者其传统风险生物标志物未得到控制。兵役有其自身的特殊性,可能会增加心血管疾病风险。

方法

为了确定预防策略目标,我们分析了塞尔维亚共和国现役军人中冠状动脉疾病的传统心血管危险因素和纤维蛋白原升高的患病率。

结果

这项横断面研究纳入了738名20岁以上的个体,大多数年龄在31至40岁之间。整个组的收缩压平均值为122.39±9.42 mmHg,舒张压平均值为79.94±6.56 mmHg。在现役军人中,72.7%(533人)患有高血压前期,13.8%(101人)患有高血压。在观察到的年龄亚组中,体重和BMI指数均随患者年龄和胆固醇值的增加而升高。不同年龄亚组的高密度脂蛋白胆固醇值也有统计学显著差异,所有亚组中高密度脂蛋白低于1.5 mmol/L的个体比例约为85%,只有41 - 50岁年龄组较低,为76.4%。低密度脂蛋白胆固醇以及低密度脂蛋白≥3.5的个体比例随患者年龄增加,甘油三酯也呈现相同趋势。随着年龄增长,纤维蛋白原水平升高。

结论

这些关于心血管和脑血管危险因素的研究结果将有助于为这类人群制定新的一级预防方法。

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