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青年人群中血脂异常的筛查及与社会经济学因素的关联。

Screening and socioeconomic associations of dyslipidemia in young adults.

机构信息

University of South Carolina-School of Medicine-Greenville (Affiliated with PRISMA Health), 607 Grove Road, Greenville, SC, 29605, USA.

Furman University, 3300 Poinsett Highway, Greenville, SC, 29613, USA.

出版信息

BMC Public Health. 2020 Jan 28;20(1):104. doi: 10.1186/s12889-019-8099-9.

Abstract

BACKGROUND

The Southern region of the United States is home to substantial populations with obesity, dyslipidemia, and hypertriglyceridemia, while also housing a large percentage of America's minority, rural, and low socioeconomic status (SES) peoples. Adult-onset cardiovascular disease (CVD) research may be informed by investigating associations(s) between late adolescent demographic variables and lipid values. Our objective was to investigate lipid parameter associations with college-age socioeconomic status, which may improve age-specific screening algorithms for management or prevention of adult-onset CVD.

METHODS

Using an Analysis of Variance test and a general linear model, associations between gender, race/ethnicity, SES, and athletic participation on lipid parameters (VLDL-C, LDL-C, TG, TC, and HDL-C) were analyzed in 4423 private liberal arts college students enrolled in freshman-level wellness courses at Furman University in Greenville, SC. Comparative data were collected from an age-matched sample (National Health and Nutrition Examination Survey: NHANES 2003-2016). Our main outcomes were statistically significant relationships between any lipid values (TC, HDL-C, LDL-C, TG) and any demographic variables (gender, SES, ethnicity, athlete status).

RESULTS

Males demonstrated lower TC and LDL-C, and higher HDL-C values. HDL-C was highest in athletes. African-American students demonstrated healthier VLDL-C, TG, and HDL-C values. With similar distributions, the age-matched NHANES comparison group showed unhealthier values in nearly all categories.

CONCLUSIONS

College students may have better lipid health than the general population. African-Americans may have seemingly healthier lipid values than age-matched individuals independent of athletic or college enrollment which has already been demonstrated in other studies. Future research should include SES relationships in lipid screening paradigms along with other appropriate risk factors for cardiovascular disease. Based on our comparative data, pediatric health providers and researchers may consider education as a potential protective factor against poor lipid health when considering lipid screening protocols for students.

摘要

背景

美国南部地区有大量肥胖、血脂异常和高甘油三酯血症患者,同时也有很大一部分美国少数民族、农村和低收入社会经济地位(SES)人群。成人起病的心血管疾病(CVD)研究可以通过研究青少年后期人口统计学变量与血脂值之间的关联来获得信息。我们的目的是调查与大学年龄 SES 相关的血脂参数,这可能会改善针对成人起病 CVD 的特定年龄筛查算法。

方法

使用方差分析检验和一般线性模型,分析了南卡罗来纳州格林维尔弗曼大学新生健康课程中 4423 名私立文科学院学生的性别、种族/民族、SES 和运动参与与血脂参数(VLDL-C、LDL-C、TG、TC 和 HDL-C)之间的关联。比较数据来自年龄匹配的样本(国家健康和营养检查调查:NHANES 2003-2016)。我们的主要结果是任何血脂值(TC、HDL-C、LDL-C、TG)与任何人口统计学变量(性别、SES、种族、运动员身份)之间存在统计学上显著的关系。

结果

男性的 TC 和 LDL-C 较低,HDL-C 较高。运动员的 HDL-C 最高。非裔美国学生的 VLDL-C、TG 和 HDL-C 值更健康。具有相似分布的年龄匹配 NHANES 对照组在几乎所有类别中都显示出更不健康的值。

结论

大学生的血脂健康状况可能优于一般人群。非裔美国人的血脂值可能比年龄匹配的个体更健康,独立于运动或大学入学,这在其他研究中已经得到证实。未来的研究应该将 SES 关系纳入血脂筛查模式以及其他心血管疾病的适当风险因素。根据我们的比较数据,儿科保健提供者和研究人员在考虑针对学生的血脂筛查方案时,可能会考虑教育作为血脂健康不良的潜在保护因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b49/6986140/0bdb11b99e09/12889_2019_8099_Fig1_HTML.jpg

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