Pai Vivek, Trivedi Chintan R, Pai Bhujang, Swaminathan Saravana K
Division of Neuroradiology, Joint Department of Medical Imaging, University of Toronto, Toronto, Canada.
Department of Radiology, Apollo Hospitals-Navi Mumbai, Mumbai, Maharashtra, India.
J Clin Imaging Sci. 2022 Apr 27;12:20. doi: 10.25259/JCIS_24_2022. eCollection 2022.
Amyotrophic Lateral Sclerosis (ALS) is a rare, devastating motor neuron disease characterized by the degeneration of upper and lower motor neurons causing muscular weakness, paralysis, and eventual death. MRI plays a supportive role in the diagnosis; its primary role is to exclude other clinical mimics. Some of the imaging features associated with ALS include hypointense signal along the motor cortices on susceptibility or T2*-weighted imaging and hyperintensity along the corticospinal tracts (CST) within the cerebral hemispheres, brainstem, and spinal cord on the T2 weighted imaging. In this report, we discuss the value of T1 hyperintensity along the CST, especially in the spinal cord.
肌萎缩侧索硬化症（ALS）是一种罕见的、具有毁灭性的运动神经元疾病，其特征是上下运动神经元退化，导致肌肉无力、瘫痪并最终死亡。MRI在诊断中起辅助作用；其主要作用是排除其他临床疑似病症。与ALS相关的一些影像学特征包括在磁敏感加权成像或T2*加权成像上运动皮质呈低信号，以及在T2加权成像上大脑半球、脑干和脊髓内的皮质脊髓束（CST）呈高信号。在本报告中，我们讨论了沿CST尤其是脊髓的T1高信号的价值。
