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人种和种族对胸主动脉腔内修复术后结局的影响。

Impact of ethnicity and race on outcomes after thoracic endovascular aortic repair.

机构信息

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

出版信息

J Card Surg. 2022 Aug;37(8):2317-2323. doi: 10.1111/jocs.16580. Epub 2022 May 5.

Abstract

INTRODUCTION

Thoracic endovascular aortic repair (TEVAR) became the standard of care for treating Type B aortic dissections and descending thoracic aortic aneurysms. We aimed to describe the racial/ethnic differences in TEVAR utilization and outcomes.

METHODS

The National Inpatient Sample was reviewed for all TEVARs performed between 2010 and 2017 for Type B aortic dissection and descending thoracic aortic aneurysm (DTAA). We compared groups stratifying by their racial/ethnicity background in White, Black, Hispanic, and others. Mixed-effects logistic regression was performed to assess the relationship between race/ethnicity and the primary outcome, in-hospital mortality.

RESULTS

A total of 25,260 admissions for TEVAR during 2010-2017 were identified. Of those, 52.74% (n = 13,322) were performed for aneurysm and 47.2% (n = 11,938) were performed for Type B dissection. 68.1% were White, 19.6% were Black, 5.7% Hispanic, and 6.5% were classified as others. White patients were the oldest (median age 71 years; p < .001), with TEVAR being performed electively more often for aortic aneurysm (58.8% vs. 34% vs. 48.3% vs. 48.2%; p < .001). In contrast, TEVAR was more likely urgent or emergent for Type B dissection in Black patients (65.6% vs. 41.1% vs. 51.6% vs. 51.7%; p < .001). Finally, the Black population showed a relative increase in the incidence rate of TEVAR over time. The adjusted multivariable model showed that race/ethnicity was not associated with in-hospital mortality.

CONCLUSION

Although there is a differential distribution of thoracic indication and comorbidities between race/ethnicity in TEVAR, racial disparities do not appear to be associated with in-hospital mortality after adjusting for covariates.

摘要

简介

胸主动脉腔内修复术(TEVAR)已成为治疗 B 型主动脉夹层和降主动脉夹层动脉瘤的标准治疗方法。我们旨在描述 TEVAR 利用和结果的种族/民族差异。

方法

回顾了 2010 年至 2017 年期间因 B 型主动脉夹层和降主动脉夹层动脉瘤(DTAA)而行 TEVAR 的所有患者的国家住院患者样本。我们按其种族/民族背景将患者分为白人、黑人、西班牙裔和其他人群进行比较。混合效应逻辑回归用于评估种族/民族与主要结局(院内死亡率)之间的关系。

结果

共确定了 2010 年至 2017 年期间 25260 例 TEVAR 入院患者。其中,52.74%(n=13322)为动脉瘤,47.2%(n=11938)为 B 型夹层。68.1%为白人,19.6%为黑人,5.7%为西班牙裔,6.5%为其他人群。白人患者年龄最大(中位数年龄 71 岁;p<.001),主动脉瘤行 TEVAR 更多为择期(58.8%比 34%比 48.3%比 48.2%;p<.001)。相反,黑人患者行 TEVAR 更多为紧急或紧急情况(65.6%比 41.1%比 51.6%比 51.7%;p<.001)。最后,黑人人群的 TEVAR 发生率随时间呈相对增加。调整后的多变量模型显示,种族/民族与院内死亡率无关。

结论

尽管在 TEVAR 中种族/民族之间存在胸主动脉适应证和合并症的差异分布,但在调整协变量后,种族差异似乎与院内死亡率无关。

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