Gu Y X, Chen M, Wang K J
Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Zhonghua Yan Ke Za Zhi. 2022 May 11;58(5):390-395. doi: 10.3760/cma.j.cn112142-20211103-00516.
Retinal ganglion cells (RGCs) are the most important type of neurons in the visual pathway. RGC axons exit the eye to form the optic nerve, which connects with the brain. The visual signals carried by RGC axons establish the only link between the outside world and our internal perception of sight. Researches on the morphological, physiological, molecular, and mosaic features of RGCs are of great significance. This article reviews the research advances of RGC classifications, definitive types of RGCs, and selective vulnerability of specific RGC types after various injuries.
视网膜神经节细胞（RGCs）是视觉通路中最重要的神经元类型。RGC轴突离开眼球形成视神经，视神经与大脑相连。RGC轴突携带的视觉信号建立了外界与我们内部视觉感知之间的唯一联系。对RGCs的形态、生理、分子和镶嵌特征的研究具有重要意义。本文综述了RGC分类、RGC的确定类型以及各种损伤后特定RGC类型的选择性易损性的研究进展。
