Helfgott Research Institute, National University of Natural Medicine, Portland, Oregon, USA.
Faculty of Medicine and Health, School of Pharmacy, The University of Sydney, Sydney, Australia.
BMC Complement Med Ther. 2022 May 5;22(1):127. doi: 10.1186/s12906-022-03582-5.
The International Cohort on Lifestyle Determinants of Health (INCLD Health) is an ongoing, prospective cohort study assessing the health behaviours and lifestyles of higher education students, including their use of specialty diets and complementary and integrative health (CIH) practices.
This cross-sectional analysis of the INCLD Health cohort aims to (1) evaluate the associations between perceived stress, sleep disturbance, and meditative practices with diurnal salivary free cortisol and (2) evaluate the associations of meditative practices as well as mind-body practices with perceived stress and sleep disturbance.
Serial multivariable linear regression models, adjusting for sociodemographic and lifestyle behaviours, were used to assess associations of (1) perceived stress, sleep disturbance, and meditative practices with salivary cortisol, and (2) meditative practices as well as mind-body practices with perceived stress and sleep disturbance. Meditative and mind-body practices were evaluated using a stress-management and self-care survey; perceived stress and sleep disturbance were evaluated using the 10-item Perceived Stress Scale (PSS), and the patient reported outcome measures information system-29 (PROMIS-29) sleep sub-score respectively. Salivary cortisol was collected at 4 time points over a 24-hour period and area under the curve (AUC) calculations conducted.
82.5% (n = 80) of participants utilized at least monthly meditative practices. Greater disturbed sleep, but not perceived-stress, meditative, nor mind-body practices was independently associated with increased AUC cortisol (b = 0.02, 95% CI: 0.002-0.05, p = 0.03) after adjusting for age, sex, race, ethnicity, and BMI. Neither meditative nor mind-body practices were associated with perceived stress or disturbed sleep.
Among INCLD Health participants, greater sleep disturbance, but not perceived stress or meditative practices were associated with daytime cortisol.
国际生活方式决定健康因素队列研究(INCLD Health)是一项正在进行的前瞻性队列研究,评估高等教育学生的健康行为和生活方式,包括他们对特殊饮食和补充及整合健康(CIH)实践的使用。
本研究对 INCLD Health 队列进行了横断面分析,旨在(1)评估感知压力、睡眠障碍和冥想练习与日间唾液游离皮质醇的关系,(2)评估冥想练习以及身心实践与感知压力和睡眠障碍的关系。
使用多变量线性回归模型,调整社会人口统计学和生活方式行为,评估(1)感知压力、睡眠障碍和冥想练习与唾液皮质醇的关系,(2)冥想练习以及身心实践与感知压力和睡眠障碍的关系。冥想和身心实践是使用应激管理和自我保健调查进行评估的;感知压力和睡眠障碍分别使用 10 项感知压力量表(PSS)和患者报告的结果测量信息系统-29(PROMIS-29)睡眠子量表进行评估。在 24 小时内采集 4 个时间点的唾液皮质醇并进行曲线下面积(AUC)计算。
82.5%(n=80)的参与者每月至少使用一次冥想练习。在调整年龄、性别、种族、民族和 BMI 后,更多的睡眠障碍,而不是感知压力、冥想或身心实践与 AUC 皮质醇增加独立相关(b=0.02,95%CI:0.002-0.05,p=0.03)。冥想和身心实践均与感知压力或睡眠障碍无关。
在 INCLD Health 参与者中,睡眠障碍程度增加与日间皮质醇有关,而感知压力或冥想练习程度增加与日间皮质醇无关。