Falkenhagen U, Becziczka B, Gotthardt H J, Speckin K U, Straube E
Z Urol Nephrol. 1986 Nov;79(11):629-36.
In 30 patients with a non-obstructive chronic pyelonephritis and two to three clinically manifest urinary tract infections per year as well as in 50 healthy test persons we determined the rate of phagocytosis and the index of phagocytosis of neutrophil granulocytes in absence of serum with Candida albicans and latex particles in double disposition. The mean values of the phagocytosis rate und phagocytosis index of the patients were significantly decreased both for Candida albicans with 40.80% and 1.29 and for latex particles with 67.80% and 2.33 compared with healthy test persons with 54.24% and 1.69 and 86.54% and 3.51, respectively, disturbances of the cell metabolism of the neutrophil granulocytes with an impairment of the function of the cell membrane were discussed as cause of the reduced effect of phagocytosis.
在30例患有非阻塞性慢性肾盂肾炎且每年有两到三次临床明显尿路感染的患者以及50名健康受试人员中,我们以双重配置,在无血清的情况下,测定了白色念珠菌和乳胶颗粒存在时中性粒细胞的吞噬率和吞噬指数。与健康受试人员相比,患者对于白色念珠菌的吞噬率和吞噬指数平均值显著降低,分别为40.80%和1.29,而健康受试人员为54.24%和1.69;对于乳胶颗粒,患者的吞噬率和吞噬指数平均值分别为67.80%和2.33,而健康受试人员为86.54%和3.51。中性粒细胞的细胞代谢紊乱以及细胞膜功能受损被讨论为吞噬作用效果降低的原因。