Baran E, Steuden W, Wasik F, Walów B, Ziarkiewicz M
Przegl Dermatol. 1989 Sep-Dec;76(5-6):391-8.
Using morphological and radionuclide methods the ability of engulfing and intracellular killing of Candida albicans cells by granulocytes of patients with atopic dermatitis was tested. The patients had moderately intense lesions without secondary infections. The results obtained by the morphological method, that is the percent of phagocytizing granulocytes, the percent of C. albicans cells engulfed by the granulocytes and the percent of killed C. albicans cells in the group of 25 patients and in the group of 25 controls were not statistically significantly different. The radionuclide method with 51Cr labelling of Candida albicans failed to demonstrate differences between 15 patients and 25 controls in the intracellular killing of these cells. No significant effect of the serum of healthy subjects on the functions of the granulocytes and no effect of the serum of the patients on granulocyte functions of controls were noted.
采用形态学和放射性核素方法，对特应性皮炎患者粒细胞吞噬白色念珠菌细胞及细胞内杀伤的能力进行了检测。患者有中度严重的皮损，无继发感染。通过形态学方法得出的结果，即25例患者组和25例对照组中吞噬粒细胞的百分比、粒细胞吞噬的白色念珠菌细胞百分比以及被杀死的白色念珠菌细胞百分比，在统计学上无显著差异。用51Cr标记白色念珠菌的放射性核素方法未能显示15例患者和25例对照组在这些细胞的细胞内杀伤方面存在差异。未观察到健康受试者血清对粒细胞功能有显著影响，也未观察到患者血清对对照组粒细胞功能有影响。
