Wang Guanhua, Hong Zhikai, Lei Yongqian
College of Veterinary Medicine, South China Agricultural University Guangzhou 510642 Guangdong PR China
Guangdong Provincial Key Laboratory of Emergency Test for Dangerous Chemicals, Guangdong Engineering Technology Research Center of On-line Monitoring of Water Environmental Pollution, Guangdong Institute of Analysis Guangzhou 510070 PR China
RSC Adv. 2020 Sep 30;10(59):35941-35948. doi: 10.1039/d0ra04101g. eCollection 2020 Sep 28.
A novel covalent triazine-based organic framework (CTF), SCAU-2, was fabricated and used as an adsorbent for the solid-phase extraction of fourteen kinds of sulfonamides (SAs) from meat. Another CTF, SCAU-1, was adopted as a comparison material, as it has a similar motif. A series of structural characterization steps was carried out on the synthesized materials and several parameters were investigated during the extraction process, including the amount of adsorbent, the dilution ratio, the pH of the sample, and the washing and elution solvents. After detection with UHPLC-Q/TOF-MS/MS, the results revealed that SCAU-2 showed high extraction efficiencies towards the selected SAs. The LOD values are from 0.05 to 0.54 ng g, and the recoveries are from 84.1% to 91.9%, with RSDs ranging from 3.2% to 4.8% for SCAU-2 when spiked at 50 ng g. The results demonstrated that the proposed method has good applicability for the determination of SAs in complicated samples.
制备了一种新型的基于共价三嗪的有机框架材料（CTF）SCAU - 2，并将其用作从肉类中固相萃取14种磺胺类药物（SAs）的吸附剂。选用另一种具有相似结构单元的CTF材料SCAU - 1作为对比材料。对合成材料进行了一系列结构表征步骤，并在萃取过程中研究了几个参数，包括吸附剂用量、稀释倍数、样品pH值以及洗涤和洗脱溶剂。经超高效液相色谱 - 四极杆/飞行时间串联质谱（UHPLC - Q/TOF - MS/MS）检测，结果表明SCAU - 2对所选磺胺类药物具有较高的萃取效率。当加标量为50 ng/g时，SCAU - 2的检出限为0.05至0.54 ng/g，回收率为84.1%至91.9%，相对标准偏差（RSD）为3.2%至4.8%。结果表明，该方法对复杂样品中磺胺类药物的测定具有良好的适用性。
