Lukin A A, Rozov A N, Planutene M V
Antibiot Med Biotekhnol. 1986 Dec;31(12):886-9.
Sporulation and synthesis of bacitracin, a peptide antibiotic and serine exoproteases and endoproteases were studied in 6 strains of Bacillus licheniformis at various periods of cultivation in sporulation media. Thermostable spores in all the strains were shown to form in the absence of both the exogenic and endogenic antibiotic and proteases. It was suggested that bacitracin and the serine proteases were not specific regulators of sporogenesis in B. licheniformis and their biological function under the natural conditions included, respectively, the antibiotic action and hydrolysis of proteins and peptides of the environment and cells.
在芽孢形成培养基中，于不同培养时期，对6株地衣芽孢杆菌的芽孢形成、杆菌肽（一种肽类抗生素）的合成、丝氨酸外切蛋白酶和内切蛋白酶进行了研究。结果表明，在没有外源性和内源性抗生素及蛋白酶的情况下，所有菌株均能形成耐热孢子。有人提出，杆菌肽和丝氨酸蛋白酶并非地衣芽孢杆菌芽孢形成的特异性调节因子，它们在自然条件下的生物学功能分别包括抗生素作用以及对环境和细胞中蛋白质和肽的水解作用。
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