Elgendy Fares, Rio-Pertuz Gaspar Del, Nguyen Dalena, Payne Drew
Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.
Proc (Bayl Univ Med Cent). 2022 Feb 2;35(3):385-386. doi: 10.1080/08998280.2022.2030188. eCollection 2022.
Methemoglobinemia is a blood disorder in which red blood cells contain methemoglobin, a form of hemoglobin that contains iron in its oxidized state, at levels >1%, often leading to a hypoxic state. It can be acquired or congenital and has been associated with nitrate or nitrite exposure. "Poppers" and "Rush" are slang terms given to drugs of the chemical class called amyl nitrate or isobutyl nitrite, which are typically inhaled and can be found over the counter. They are used with the intention of enhancing sexual performance due to their vasodilator effects, anal sphincter relaxation, and aphrodisia. We report a case of a man who developed methemoglobinemia secondary to "popper" abuse.
高铁血红蛋白血症是一种血液疾病,其中红细胞含有高铁血红蛋白,这是一种血红蛋白形式,其铁处于氧化状态,含量>1%,常导致缺氧状态。它可以是后天获得的或先天性的,并且与硝酸盐或亚硝酸盐暴露有关。“Poppers”和“Rush”是对化学类别为亚硝酸戊酯或亚硝酸异丁酯的药物的俚语称呼,这些药物通常通过吸入使用,且可在柜台购买到。由于它们的血管舒张作用、肛门括约肌松弛作用和催情作用,人们使用它们来增强性功能。我们报告一例因滥用“Poppers”继发高铁血红蛋白血症的男性病例。