Curry S
Ann Emerg Med. 1982 Apr;11(4):214-21. doi: 10.1016/s0196-0644(82)80502-7.
Methemoglobinemia must be considered in the differential diagnosis of the cyanotic patient. Methemoglobin cannot carry oxygen or carbon dioxide. Methemoglobinemia can result from exposure to a wide variety of chemicals, including many commonly prescribed drugs, usually in an overdose situation. Most cases require only supportive therapy and assessment for other toxic complications. Severe cases may result in hypoxia and require treatment with methylene blue. Not all cases respond to methylene blue, and methylene blue itself may produce serious side effects.
在对发绀患者进行鉴别诊断时，必须考虑高铁血红蛋白血症。高铁血红蛋白不能携带氧气或二氧化碳。高铁血红蛋白血症可由接触多种化学物质引起，包括许多常用处方药，通常是在过量使用的情况下。大多数病例仅需支持性治疗并评估其他中毒并发症。严重病例可能导致缺氧，需要用亚甲蓝治疗。并非所有病例对亚甲蓝都有反应，而且亚甲蓝本身可能会产生严重的副作用。
