Rodriguez Connor, Dhaliwal Parneet, Readinger Allison
Texas Christian University School of Medicine, Fort Worth, Texas.
Department of Pathology, Baylor University Medical Center, Dallas, Texas.
Proc (Bayl Univ Med Cent). 2022 Feb 24;35(3):348-349. doi: 10.1080/08998280.2022.2039047. eCollection 2022.
Secondary syphilis can present with a diffuse, nonpruritic, contagious skin rash. The most common presentation of the rash consists of reddish-brown macules and papules seen on the palms and soles, often with papules and plaques on the torso and proximal extremities. However, the presentation may also include warty or raised mucous membrane lesions or patchy alopecia. In this case, we present a patient with rupioid syphilis, an atypical cutaneous manifestation of malignant secondary syphilis. Further, this case illustrates atypical biopsy findings in patients with rupioid syphilis. The variety of cutaneous and histologic presentations in secondary syphilis can make it challenging to identify the cause of the rash.
二期梅毒可表现为弥漫性、无瘙痒、具有传染性的皮疹。皮疹最常见的表现为手掌和足底出现红棕色斑疹和丘疹，躯干和近端肢体常出现丘疹和斑块。然而，其表现也可能包括疣状或隆起的黏膜损害或斑片状脱发。在此，我们报告一例蛎壳状梅毒患者，这是恶性二期梅毒的一种非典型皮肤表现。此外，该病例说明了蛎壳状梅毒患者的非典型活检结果。二期梅毒皮肤和组织学表现的多样性可能使其皮疹病因的确定具有挑战性。
