Yadav Jitendra Kumar, Yadav Priyanka, Awasthi Satish K, Agarwal Alka
Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University Varanasi UP India
Chemical Biology Laboratory, Department of Chemistry, University of Delhi Delhi Delhi-110007 India
RSC Adv. 2020 Nov 12;10(67):41229-41236. doi: 10.1039/d0ra07476d. eCollection 2020 Nov 9.
Sulfonic acid functionalized over biguanidine fabricated silica-coated heterogeneous magnetic nanoparticles (NP@SOH) have been synthesized, well characterized and explored for the first time, as an efficient and recyclable catalyst for -formylation of primary amines under mild reaction conditions. Exploiting the magnetic nature of FeO, the prepared catalyst was readily recovered from the reaction mixture an external magnet. The catalyst can be reused for up to six cycles without any substantial loss of catalytic activity. The cost effectiveness, simple methodology, wide substrate tolerance, excellent yield and easy work-up are the additional advantages of present catalytic system.
磺酸官能化双胍修饰的二氧化硅包覆的非均相磁性纳米粒子（NP@SOH）首次被合成、充分表征并进行探索，作为一种在温和反应条件下用于伯胺甲酰化的高效且可回收的催化剂。利用FeO的磁性，制备的催化剂可通过外部磁铁轻松从反应混合物中回收。该催化剂可重复使用多达六个循环，而催化活性没有任何实质性损失。成本效益、简单的方法、广泛的底物耐受性、优异的产率和易于后处理是本催化体系的其他优点。
