Gilboa E
Bioessays. 1986 Dec;5(6):252-7. doi: 10.1002/bies.950050605.
Retroviral vectors utilize the biochemical processes unique to retroviruses, to transfer genes with high efficiency into a wide variety of cell types in tissue culture and in living animals. With such vectors, the effect of newly introduced genes and the mechanism of gene expression can be studied in cell types so far refractory to other methods of transfer.
逆转录病毒载体利用逆转录病毒特有的生化过程,将基因高效转移到组织培养和活体动物中的多种细胞类型中。利用这些载体,可以在迄今为止对其他转移方法具有抗性的细胞类型中研究新导入基因的作用和基因表达机制。