Al-Azemi Talal F, Vinodh Mickey, Alipour Fatemeh H, Mohamod Abdirahman A
Chemistry Department, Kuwait University P. O. Box 5969, Safat 13060 Kuwait
RSC Adv. 2019 May 3;9(24):13814-13819. doi: 10.1039/c9ra02313e. eCollection 2019 Apr 30.
We herein report the preparation of constitutional isomers of brominated-functionalized pillar[5]arenes co-condensation of 1,4-bis(2-bromoethoxy)benzene and 1,4-dimethoxybenzene. The structures of the obtained isomers were then established using single crystal X-ray diffraction. We also found that the isomeric yield distribution of the different constitutional isomers was independent of the monomer's mole feed ratio, as revealed by HPLC analysis of the crude mixture. Finally, further characterization of the separated constitutional isomers indicated that they possess different melting points, NMR spectra, crystal structures, binding constants and stacking patterns in the solid state.
我们在此报告了溴化功能化柱[5]芳烃的构造异构体的制备——1,4-双(2-溴乙氧基)苯与1,4-二甲氧基苯的共缩合反应。然后通过单晶X射线衍射确定了所得异构体的结构。我们还发现，通过对粗混合物的HPLC分析表明，不同构造异构体的异构产率分布与单体的摩尔进料比无关。最后，对分离出的构造异构体的进一步表征表明，它们具有不同的熔点、核磁共振谱、晶体结构、结合常数以及固态下的堆积模式。
