School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, China.
Org Biomol Chem. 2011 Oct 21;9(20):7007-10. doi: 10.1039/c1ob05871a. Epub 2011 Aug 25.
An efficient method for the synthesis of copillar[5]arenes was developed with FeCl(3) as catalyst and different 1,4-dialkoxybenzenes and paraformaldehyde as reactants (yields: 50-85%). The host-guest property of (co)pillar[5]arenes and terminal dibromoalkanes was investigated by (1)H NMR measurements and an X-ray study. The complexation behavior of the copillar[5]arenes can be tuned by changing the substituents on the host. A complete complexation selectivity was found between pillar[5]- and pillar[6]arenes, which is an interesting aspect for sensor techniques.
开发了一种使用 FeCl(3) 作为催化剂，不同的 1,4-二烷氧基苯和多聚甲醛作为反应物合成 copillar[5]芳烃的有效方法（产率：50-85%）。通过（1）H NMR 测量和 X 射线研究研究了（co）pillar[5]芳烃和末端二溴代烷烃的主客体性质。通过改变主体上的取代基可以调节 copillar[5]芳烃的络合行为。在传感器技术方面，发现了 pillar[5]-和 pillar[6]-芳烃之间完全的络合选择性，这是一个有趣的方面。
