Kojima Shigeko, Saito Ayako, Sasaki Fumihiko, Hayashi Masamichi, Mieno Yuki, Sakakibara Hiroki, Hashimoto Shuji
Department of Rehabilitation, Faculty of Health Sciences, Nihon Fukushi University, Handa, Aichi, Japan.
Department of Hygiene, School of Medicine, Fujita Heath University, Toyoake, Aichi, Japan.
Fujita Med J. 2022 May;8(2):37-41. doi: 10.20407/fmj.2020-028. Epub 2021 Aug 20.
We conducted a retrospective study among 497 male patients with OSA on CPAP therapy. Participants with pretreatment Apnea-Hypopnea Index (AHI) data based on overnight polysomnographic recordings completed a questionnaire. Adherence data for CPAP therapy were collected using a smart card system. We classified CPAP use of ≥4 hours per night and ≥70% of nights as good adherence; other CPAP use was categorized as poor adherence. Logistic regression models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for poor adherence to CPAP therapy in the hypertension and diabetes mellitus groups, compared with the no comorbidity group, adjusting for body mass index, duration of CPAP therapy, AHI, and Epworth Sleepiness Scale score.
In the no comorbidity, hypertension, and diabetes mellitus groups, 43.4%, 44.7%, and 56.0%, respectively, had poor adherence to CPAP therapy. Being in the diabetes mellitus group was significantly associated with poor adherence to CPAP therapy (OR=1.86, 95% CI: 1.18-2.92, =0.007); there was no association for the hypertension group.
Our results indicate that comorbidity of diabetes mellitus is associated with poor adherence to CPAP therapy in male patients with OSA.
我们对497名接受持续气道正压通气（CPAP）治疗的阻塞性睡眠呼吸暂停（OSA）男性患者进行了一项回顾性研究。根据夜间多导睡眠图记录，有治疗前呼吸暂停低通气指数（AHI）数据的参与者完成了一份调查问卷。使用智能卡系统收集CPAP治疗的依从性数据。我们将每晚使用CPAP≥4小时且≥70%的夜晚定义为依从性良好；其他CPAP使用情况归类为依从性差。使用逻辑回归模型计算高血压组和糖尿病组与无合并症组相比CPAP治疗依从性差的比值比（OR）和95%置信区间（CI），并对体重指数、CPAP治疗持续时间、AHI和爱泼华嗜睡量表评分进行校正。
在无合并症组、高血压组和糖尿病组中，分别有43.4%、44.7%和56.0%的患者CPAP治疗依从性差。糖尿病组与CPAP治疗依从性差显著相关（OR=1.86，95%CI：1.18-2.92，P=0.007）；高血压组无相关性。
我们的结果表明，糖尿病合并症与男性OSA患者CPAP治疗依从性差有关。
