Li Zhijian, Gong Congcong, Huo Panpan, Deng Chunhui, Pu Shouzhi
Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University Nanchang 330013 PR China
Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, Department of Environmental Science and Engineering, Fudan University Shanghai 200433 China.
RSC Adv. 2020 Aug 5;10(49):29061-29067. doi: 10.1039/d0ra04125d.
Microcystin-LR (MC-LR) is a toxin released from cyanobacteria in eutrophicated water. MC-LR is the most abundant and the most toxic among microcystins. In this work, core-shell structured copper-based magnetic metal-organic framework (FeO@PDA@Cu-MOFs) composites were synthesized a solvothermal reaction and a sol-gel method. The FeO@PDA@Cu-MOFs composites showed ultra-high surface area, strong magnetic response and outstanding hydrophilicity. The FeO@PDA@Cu-MOFs composites combined with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF-MS) were used to analyse the content of MC-LR in real water samples. Under the optimised conditions, our proposed method exhibited good linearity within a concentration range of 0.05-4 μg L and good detection even at low limits (0.015 μg L). The method was also successfully applied to analyse traces of MC-LR with quantitative recoveries for the real water samples in the range from 98.67% to 106.15%. Furthermore, it was characterized by high sensitivity, short operation time, being environmental friendly and having the ability to analyse other pollutants in the environment.
微囊藻毒素-LR（MC-LR）是富营养化水体中蓝藻释放的一种毒素。MC-LR是微囊藻毒素中毒性最强且含量最高的一种。在本研究中，通过溶剂热反应和溶胶-凝胶法合成了核壳结构的铜基磁性金属有机框架（FeO@PDA@Cu-MOFs）复合材料。FeO@PDA@Cu-MOFs复合材料具有超高的比表面积、强磁响应性和出色的亲水性。将FeO@PDA@Cu-MOFs复合材料与基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF-MS）联用，用于分析实际水样中MC-LR的含量。在优化条件下，所提出的方法在0.05-4 μg/L的浓度范围内具有良好的线性，即使在低限（0.015 μg/L）也具有良好的检测效果。该方法还成功应用于分析痕量MC-LR，实际水样的定量回收率在98.67%至106.15%之间。此外，该方法具有灵敏度高、操作时间短、环境友好以及能够分析环境中其他污染物的特点。
