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牛中枢神经系统的先天性缺陷。

Congenital defects of the bovine central nervous system.

作者信息

Leipold H W, Dennis S M

出版信息

Vet Clin North Am Food Anim Pract. 1987 Mar;3(1):159-77. doi: 10.1016/s0749-0720(15)31188-9.

Abstract

Congenital brain defects in cattle are usually obvious at birth, but detection may depend on the nature and extent of the defect. The cause may be genetic or environmental, or the cause may be unknown. Many central nervous system defects are inherited as a simple autosomal recessive trait and may have a significant economic impact on purebred and commercial cattle operations. A common structural defect of genetic nature is internal hydrocephalus. A functional defect of simple autosomal recessive inheritance is bovine progressive degenerative myeloencephalopathy. The most significant teratogenic agents causing central nervous system defects are prenatal viral infections such as bovine virus diarrhea and bluetongue viruses. Many other defects of the central nervous system are reviewed.

摘要

牛的先天性脑缺陷通常在出生时就很明显,但检测可能取决于缺陷的性质和程度。其病因可能是遗传的或环境的,也可能原因不明。许多中枢神经系统缺陷以简单的常染色体隐性性状遗传,可能对纯种和商业养牛业产生重大经济影响。一种常见的遗传性结构缺陷是内部脑积水。一种简单的常染色体隐性遗传的功能性缺陷是牛进行性变性脊髓脑病。导致中枢神经系统缺陷的最重要致畸因素是产前病毒感染,如牛病毒性腹泻和蓝舌病毒。本文还综述了许多其他中枢神经系统缺陷。

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