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气管支气管软化症和过度动态性气道塌陷:当前概念和未来方向。

Tracheobronchomalacia and Excessive Dynamic Airway Collapse: Current Concepts and Future Directions.

机构信息

From the Department of Radiology, Division of Cardiothoracic Imaging (A.A., E.C.S., E.L., P.P.A.), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Section of Thoracic Surgery, Department of Surgery (J.D.L.C.), Department of Otolaryngology-Head and Neck Surgery (R.J.M.), Department of Surgery (K.H.L.), Michigan Medicine, 1500 E Medical Center Dr, Ann Arbor, MI 48109; Department of Surgery, Ann Arbor Veterans Hospital, Ann Arbor, Mich (K.H.L.); and Department of Radiology, Division of Cardiothoracic Imaging, Beth Israel Deaconess Medical Center, Boston, Mass (D.L.).

出版信息

Radiographics. 2022 Jul-Aug;42(4):1012-1027. doi: 10.1148/rg.210155. Epub 2022 May 6.

Abstract

Tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC) are airway abnormalities that share a common feature of expiratory narrowing but are distinct pathophysiologic entities. Both entities are collectively referred to as expiratory central airway collapse (ECAC). The or weakness of cartilage that supports the tracheobronchial tree may occur only in the trachea (ie, tracheomalacia), in both the trachea and bronchi (TBM), or only in the bronchi (bronchomalacia). On the other hand, EDAC refers to excessive anterior bowing of the posterior membrane into the airway lumen with intact cartilage. Clinical diagnosis is often confounded by comorbidities including asthma, chronic obstructive pulmonary disease, obesity, hypoventilation syndrome, and gastroesophageal reflux disease. Additional challenges include the underrecognition of ECAC at imaging; the interchangeable use of the terms and in the literature, which leads to confusion; and the lack of clear guidelines for diagnosis and treatment. The use of CT is growing for evaluation of the morphology of the airway, tracheobronchial collapsibility, and extrinsic disease processes that can narrow the trachea. MRI is an alternative tool, although it is not as widely available and is not used as frequently for this indication as is CT. Together, these tools not only enable diagnosis, but also provide a road map to clinicians and surgeons for planning treatment. In addition, CT datasets can be used for 3D printing of personalized medical devices such as stents and splints. RSNA, 2022.

摘要

气道软化症(TBM)和过度动态气道塌陷(EDAC)是气道异常,具有呼气性气道狭窄的共同特征,但属于不同的病理生理实体。这两种实体统称为呼气性中央气道塌陷(ECAC)。气道支撑软骨的 或无力可能仅发生在气管(即气管软化症)、气管和支气管(TBM)、或仅发生在支气管(支气管软化症)。另一方面,EDAC 是指后膜过度向前弯曲进入气道腔,而软骨完整。临床诊断常因合并症而复杂化,包括哮喘、慢性阻塞性肺疾病、肥胖、通气不足综合征和胃食管反流病。其他挑战包括在影像学上对 ECAC 认识不足;文献中 和 这两个术语的互换使用,导致混淆;以及缺乏明确的诊断和治疗指南。CT 越来越多地用于评估气道形态、气管支气管可塌陷性以及可能使气管变窄的外在疾病过程。磁共振成像(MRI)是一种替代工具,尽管它不如 CT 广泛可用,也不如 CT 常用于该指征。这些工具不仅有助于诊断,还为临床医生和外科医生提供了治疗计划的路线图。此外,CT 数据集可用于 3D 打印个性化医疗器械,如支架和夹板。放射学学会,2022 年。

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