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颌面部位原发性动脉瘤样骨囊肿的临床放射学特征:系列病例 31 例。

Clinicoradiological spectrum of primary aneurysmal bone cysts of the maxillofacial region: A series of 31 cases.

机构信息

Department of Oral Pathology and Oral Biology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.

出版信息

Dentomaxillofac Radiol. 2022 Jul 1;51(5):20220071. doi: 10.1259/dmfr.20220071. Epub 2022 May 23.

Abstract

OBJECTIVES

The aim of the current study was to analyse the demographic, clinical and radiological features of primary aneurysmal bone cysts (ABCs) involving the maxillofacial region.

METHODS

Histologically confirmed cases affecting the maxillofacial region were retrospectively reviewed over a 21-year period (2000-2021). Cases were collected from the archives of five Oral Pathology laboratories from three countries: South Africa, Guatemala and Brazil. The information was analysed, with emphasis on the clinical and radiological spectrum.

RESULTS

Following the inclusion criteria, a total of 31 cases of primary ABCs were included in the study. A nearly equal male-to-female distribution was seen, with ABCs occurring in males at an earlier age compared to females. Localised swelling was the main clinical presentation. ABCs had a mandibular predominance, particularly in the posterior regions. All ABCs presented as blow-out expansile well-demarcated radiolucent lesions with the majority having a multilocular appearance. Cortical expansion was seen in 91% of cases with loss of cortical integrity being common (78%).

CONCLUSION

Primary ABCs involving the maxillofacial region are extremely rare with the majority of current published literature consisting of isolated case reports. The current study is the first large series detailing the radiological features.

摘要

目的

本研究旨在分析发生于颌面区域的原发性骨巨细胞瘤(ABC)的人口统计学、临床和影像学特征。

方法

回顾性分析了 21 年间(2000 年至 2021 年)五个口腔病理实验室从三个国家(南非、危地马拉和巴西)收集的经组织学证实的颌面区域受累病例。分析了这些病例的信息,重点关注临床和放射学谱。

结果

根据纳入标准,本研究共纳入 31 例原发性 ABC。男女比例几乎相等,男性 ABC 的发病年龄早于女性。局部肿胀是主要的临床表现。ABC 以下颌骨为主,特别是在后区。所有 ABC 均表现为爆裂样膨胀性界限清楚的透亮病变,大多数呈多房性外观。91%的病例有骨皮质膨胀,常见皮质完整性丧失(78%)。

结论

颌面区域原发性 ABC 极为罕见,大多数现有的文献均为孤立的病例报告。本研究是首次详细描述影像学特征的大型系列研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7f9/10043610/a67db1250a58/dmfr.20220071.g001.jpg

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