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增加非洲人群参与临床试验的策略。

Strategies to Increase Participation of African Populations in Clinical Trials.

机构信息

Center of Global Oncology and Health Equity, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN.

Institute of Translational Genomics, Department of Translational Genomics, University of Southern California, Los Angeles, CA.

出版信息

Am Soc Clin Oncol Educ Book. 2022 Apr;42:1-6. doi: 10.1200/EDBK_356481.

Abstract

Conducting clinical research in low- and middle-income countries is essential to address the global impact of cancer. In 2017, ASCO convened an Academic Global Oncology Task Force that recommended an increase in global oncology research to enhance the field of oncology through research and education. The emerging crisis of cancer in Africa demands a similar global commitment to workforce development, infrastructure building, and access to care that will provide a platform for impactful and relevant research efforts. In the words of the African Organisation for Research and Training in Cancer, it is time to "transform cancer control in Africa through collaboration in education, research, (and) delivery of equitable and timely interventions to minimize the impact of cancer." Although there are some initiatives aimed at developing research capacity to host trials in Africa, there is now a need to establish strategic partnerships with the aim of achieving harmonized, accredited clinical trial units capable of running trials according to Good Clinical Practice standards.

摘要

在中低收入国家开展临床研究对于应对癌症的全球影响至关重要。2017 年,美国临床肿瘤学会召集了一个学术全球肿瘤学工作组,该工作组建议增加全球肿瘤学研究,通过研究和教育来加强肿瘤学领域。非洲癌症的新兴危机要求全球做出类似的承诺,以发展劳动力、基础设施建设和获得医疗服务,为有影响力和相关的研究工作提供平台。正如非洲癌症研究和培训组织所说,现在是“通过教育、研究和(提供公平和及时的干预措施)来合作,改变非洲的癌症控制,以最大限度地减少癌症的影响”的时候了。尽管有一些旨在发展研究能力以在非洲主办试验的举措,但现在需要建立战略伙伴关系,目的是建立符合良好临床实践标准的协调一致、经认证的临床试验单位。

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