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本文引用的文献

1
Appropriate use of essential medicines in the elderly: a comparison of the WHO essential medicines list and PIM criteria.老年人基本药物的合理使用:世卫组织基本药物清单和 PIM 标准的比较。
Eur J Clin Pharmacol. 2021 Apr;77(4):509-516. doi: 10.1007/s00228-020-03038-0. Epub 2020 Nov 12.
2
Using Wisely: A Reminder on the Proper Use of the American Geriatrics Society Beers Criteria®.明智使用:关于正确使用美国老年医学会《Beers标准》®的提示。
J Am Geriatr Soc. 2019 Apr;67(4):644-646. doi: 10.1111/jgs.15766. Epub 2019 Jan 29.
3
American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults.美国老年医学学会 2019 年更新的老年人潜在不适当药物使用 AGS Beers 标准®。
J Am Geriatr Soc. 2019 Apr;67(4):674-694. doi: 10.1111/jgs.15767. Epub 2019 Jan 29.
4
Healthy ageing: moving forward.健康老龄化:向前迈进。
Bull World Health Organ. 2017 Nov 1;95(11):730-730A. doi: 10.2471/BLT.17.203745.
5
The EU(7)-PIM list: a list of potentially inappropriate medications for older people consented by experts from seven European countries.欧盟(7)-PIM清单:一份由七个欧洲国家的专家认可的老年人潜在不适当药物清单。
Eur J Clin Pharmacol. 2015 Jul;71(7):861-75. doi: 10.1007/s00228-015-1860-9. Epub 2015 May 14.
6
STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.老年人潜在不适当处方的STOPP/START标准:第2版
Age Ageing. 2015 Mar;44(2):213-8. doi: 10.1093/ageing/afu145. Epub 2014 Oct 16.
7
A quiet revolution in global public health: The World Health Organization's Prequalification of Medicines Programme.全球公共卫生领域的一场悄然变革:世界卫生组织药品预认证计划。
J Public Health Policy. 2014 May;35(2):137-61. doi: 10.1057/jphp.2013.53. Epub 2014 Jan 16.
8
Clinical consequences of polypharmacy in elderly.老年人药物过多的临床后果。
Expert Opin Drug Saf. 2014 Jan;13(1):57-65. doi: 10.1517/14740338.2013.827660. Epub 2013 Sep 27.
9
Inappropriate prescribing: a systematic overview of published assessment tools.不适当处方:已发表评估工具的系统综述
Eur J Clin Pharmacol. 2014 Jan;70(1):1-11. doi: 10.1007/s00228-013-1575-8. Epub 2013 Sep 10.
10
Adverse drug reactions in a population of hospitalized very elderly patients.住院高龄患者人群中的药物不良反应。
Drugs Aging. 2012 Aug 1;29(8):669-79. doi: 10.1007/BF03262282.

比较 22 届世界卫生组织基本药物标准清单与明确治疗老年患者慢性病的标准。

Comparison of the 22nd World Health Organization Model List of Essential Medicines with the explicit criteria for the treatment of chronicity in elderly patients.

机构信息

Pharmacy Department, Consorci Sociosanitari de Vilafranca, Vilafranca del Penedes, Barcelona, Spain

Pharmacy Department, Althaia Foundation of Manresa, Manresa, Catalunya, Spain.

出版信息

Eur J Hosp Pharm. 2023 Mar;30(e1):e66-e69. doi: 10.1136/ejhpharm-2022-003237. Epub 2022 May 6.

DOI:10.1136/ejhpharm-2022-003237
PMID:35523536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10086716/
Abstract

OBJECTIVES

This study analysed whether the Model List of Essential Medicines is suitable for elderly patients. Furthermore, it investigated the specific issues that should be considered when prescribing a drug and which drugs should be added to improve the list according to the explicit criteria guidelines.

METHODS

A qualitative descriptive review was performed comparing the explicit criteria guidelines of Beers 2019, Laroche, McLeod, NORGEP, PRISCUS, STOPP/START 2014 and Winit-Watjana with the 22nd edition of the Model List of Essential Medicines.

RESULTS

The Model List of Essential Medicines has 458 drugs. Depending on the explicit criteria considered, there were different numbers of potentially inappropriate medications and potential prescribing omissions. When all explicit criteria were combined, a total of 73 medicines were classified as potentially inappropriate. Using the STOPP/START criteria, 46 potential prescribing omissions were detected. According to these explicit criteria, the Model List of Essential Medicines appeared to lack some medicines.

CONCLUSIONS

Explicit criteria guidelines have different potential for detecting potentially inappropriate medications. Our findings suggest that some drugs should be added to the next edition of the Model List of Essential Medicines to cover some therapeutic gaps.

摘要

目的

本研究分析了《基本药物示范目录》是否适用于老年患者。此外,还根据明确的标准指南,研究了开具药物时应考虑的具体问题,以及应添加哪些药物以改善该目录。

方法

采用定性描述性综述方法,将 2019 年 Beers 标准、Laroche 标准、McLeod 标准、NORGEP 标准、PRISCUS 标准、STOPP/START 2014 标准和第 22 版《基本药物示范目录》的明确标准指南进行比较。

结果

《基本药物示范目录》共有 458 种药物。根据所考虑的明确标准,潜在不适当药物和潜在处方遗漏的数量不同。当综合所有明确标准时,共有 73 种药物被归类为潜在不适当。使用 STOPP/START 标准,发现了 46 种潜在的处方遗漏。根据这些明确标准,《基本药物示范目录》似乎缺乏一些药物。

结论

明确标准指南在检测潜在不适当药物方面具有不同的潜力。我们的研究结果表明,下一个版本的《基本药物示范目录》应添加一些药物,以弥补一些治疗空白。