Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan, Khon Kaen Campus, Khon Kaen 40000, Thailand.
J Chromatogr A. 2022 Jun 21;1673:463111. doi: 10.1016/j.chroma.2022.463111. Epub 2022 May 1.
A newly designed magnetic layered double hydroxide composite modified with a natural deep eutectic solvent derived from choline chloride and sucrose was synthesized and applied as a sorbent for the enrichment of organochlorine pesticides. The magnetic solid phase extraction (MSPE) procedure was optimized via a small central composite design and response surface methodology. The MSPE method was able to preconcentrate the organochlorine residues in environmental samples prior to GC-MS analysis. Good analytical performance of the proposed method was observed with an enrichment factor of up to 158 and low limits of detection in the ranges of 0.002-0.015 µg·L and 0.03-0.10 ng·g for water and soil, respectively. Satisfactory recoveries for spiked water and soil samples were obtained in the ranges of 80.9-104.7% (RSDs<7.9) and 88.8-104.1% (RSDs<7.3), respectively. This finding highlights the role of natural deep eutectic solvents as modifying agents for magnetic layered double hydroxides, which enhance the efficiency of extraction of the target analytes. The developed MSPE/GC-MS procedure was sensitive and reliable for the determination of trace organochlorine residues in environmental samples.
一种新型的磁性层状双氢氧化物复合材料，是用氯化胆碱和蔗糖合成的天然深共熔溶剂进行修饰的，被合成并应用于作为有机氯农药的富集剂。通过小中心组合设计和响应面法优化了磁固相萃取（MSPE）程序。MSPE 方法能够在 GC-MS 分析之前对环境样品中的有机氯残留进行预浓缩。该方法在水和土壤中的检测限分别为 0.002-0.015μg·L 和 0.03-0.10ng·g，具有良好的分析性能，富集因子高达 158。对于加标水和土壤样品，回收率在 80.9-104.7%（RSDs<7.9）和 88.8-104.1%（RSDs<7.3）范围内，结果令人满意。这一发现突出了天然深共熔溶剂作为磁性层状双氢氧化物修饰剂的作用，提高了目标分析物的萃取效率。开发的 MSPE/GC-MS 程序对于环境样品中痕量有机氯残留的测定具有较高的灵敏度和可靠性。
