Department of Health and Medical Informatics, Kyungnam University College of Health Sciences, Changwon, Republic of Korea; Institute for Biomedical Informatics, School of Medicine, CHA University, Seongnam, Republic of Korea.
Institute for Biomedical Informatics, School of Medicine, CHA University, Seongnam, Republic of Korea; Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, Republic of Korea; Institute of Basic Medical Sciences, School of Medicine, CHA University, Seongnam, Republic of Korea.
Environ Res. 2022 Sep;212(Pt C):113392. doi: 10.1016/j.envres.2022.113392. Epub 2022 May 5.
Air pollution and meteorological factors can exacerbate susceptibility to respiratory viral infections. To establish appropriate prevention and intervention strategies, it is important to determine whether these factors affect the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, this study examined the effects of sunshine, temperature, wind, and air pollutants including sulfur dioxide (SO), carbon monoxide (CO), ozone (O), nitrogen dioxide (NO), particulate matter ≤2.5 μm (PM), and particulate matter ≤10 μm (PM) on the age-standardized incidence ratio of coronavirus disease (COVID-19) in South Korea between January 2020 and April 2020. Propensity score weighting was used to randomly select observations into groups according to whether the case was cluster-related, to reduce selection bias. Multivariable logistic regression analyses were used to identify factors associated with COVID-19 incidence. Age 60 years or over (odds ratio [OR], 1.29; 95% CI, 1.24-1.35), exposure to ambient air pollutants, especially SO (OR, 5.19; 95% CI, 1.13-23.9) and CO (OR, 1.17; 95% CI, 1.07-1.27), and non-cluster infection (OR, 1.28; 95% CI, 1.24-1.32) were associated with SARS-CoV-2 infection. To manage and control COVID-19 effectively, further studies are warranted to confirm these findings and to develop appropriate guidelines to minimize SARS-CoV-2 transmission.
空气污染和气象因素可加重呼吸道病毒感染的易感性。为制定适当的预防和干预策略，确定这些因素是否影响严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的传播非常重要。因此，本研究调查了阳光、温度、风以及包括二氧化硫（SO）、一氧化碳（CO）、臭氧（O）、二氧化氮（NO）、≤2.5μm 颗粒物（PM）和≤10μm 颗粒物（PM）在内的空气污染物对 2020 年 1 月至 4 月韩国冠状病毒病（COVID-19）年龄标准化发病率的影响。采用倾向评分加权法根据病例是否为聚集性感染随机选择观测值进入组，以减少选择偏倚。采用多变量逻辑回归分析确定与 COVID-19 发病相关的因素。60 岁及以上（比值比 [OR]，1.29；95%置信区间，1.24-1.35）、暴露于环境空气污染物，特别是 SO（OR，5.19；95%置信区间，1.13-23.9）和 CO（OR，1.17；95%置信区间，1.07-1.27）以及非聚集性感染（OR，1.28；95%置信区间，1.24-1.32）与 SARS-CoV-2 感染相关。为了有效管理和控制 COVID-19，需要进一步研究来证实这些发现，并制定适当的指南以最大程度地减少 SARS-CoV-2 的传播。
