Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Servicio de Reumatología, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Med Clin (Barc). 2022 Jul 8;159(1):40-46. doi: 10.1016/j.medcli.2022.01.024. Epub 2022 May 4.
Psoriatic arthritis (PsA) is a type of inflammatory arthritis that is included within the spondyloarthritis, a group of rheumatological diseases characterized by different clinical manifestations and associated comorbidities, that can compromise the quality of life of patients. The diagnosis of PsA is sometimes difficult due to an enormous clinical and radiological variability, including six different domains of involvement: peripheral joint, axial skeleton, skin psoriasis, nail psoriasis, enthesitis and dactylitis. Currently, there are no biomarkers that allow the detection of PsA in patients with psoriasis, so a high level of suspicion is important, mainly by dermatologists, but also by other specialists, such as family doctors. Advances in the knowledge of new immunological mechanisms and joint management by rheumatologists and dermatologists have made it possible to improve the therapeutic approach in patients with PsA.
银屑病关节炎(PsA)是一种炎症性关节炎,属于脊柱关节炎,这是一组具有不同临床表现和相关合并症的风湿病,会影响患者的生活质量。由于临床表现和影像学表现存在巨大差异,包括六个不同的受累领域:外周关节、中轴骨骼、皮肤银屑病、指甲银屑病、附着点炎和指(趾)炎,因此 PsA 的诊断有时较为困难。目前,还没有能够在银屑病患者中检测出 PsA 的生物标志物,因此高度怀疑是很重要的,主要由皮肤科医生,但也包括其他专家,如家庭医生。风湿病学家和皮肤科医生对新的免疫学机制和关节管理的认识的提高,使得改善 PsA 患者的治疗方法成为可能。