Hamgård Nelly, Duvetorp Albert, Hägg Anna, Jerkovic Gullin Sandra, Seifert Oliver
Division of Cell Biology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Department of Dermatology and Venereology, Lund University, Skane University Hospital, Malmö, Sweden.
J Multimorb Comorb. 2023 Oct 30;13:26335565231212336. doi: 10.1177/26335565231212336. eCollection 2023 Jan-Dec.
Individuals with psoriasis face an increased risk of suffering from various comorbid conditions. However, there haven´t been any studies conducted in Sweden to examine the frequency of comorbidities and the corresponding treatment for these conditions among psoriasis patients.
The Cosmic electronic medical record represents a comprehensive repository of medical information including all residents of Region Jönköping. To conduct a population-based retrospective cross-sectional study, all individuals diagnosed with psoriasis between April 9, 2008 and July 1, 2016, were identified via the electronic medical records using ICD-10 codes. Data on comorbidity and dispensation of prescribed drugs against these comorbid conditions were analyzed.
During the study period, 1.7% of the population (4,587 individuals) were diagnosed with psoriasis, with 74.3% of cases classified as mild to moderate psoriasis and 25.7% as severe. The remaining 268,949 individuals did not receive a psoriasis diagnosis. The study showed that psoriasis patients had higher odds of experiencing the majority of the comorbid conditions examined. Arthritis other than psoriasis arthritis was found to be the most prevalent comorbid diagnosis among psoriasis patients (adjusted OR 7.2, CI 95% 6.4-8.2, p < 0.001), followed by obesity (OR 2.4, CI 95% 1.9-3.1, p < 0,001). There was no significant difference in drug prescription for comorbid diseases between patients with psoriasis and patients without psoriasis except for arthritis and smoking cessation treatment.
Individuals with psoriasis are more susceptible to experiencing multiple comorbid conditions compared to the general population, particularly those with severe psoriasis. There is no evidence of undertreatment of comorbidity except for arthritis among psoriasis patients.
银屑病患者患各种合并症的风险增加。然而，瑞典尚未开展任何研究来调查银屑病患者中合并症的发生率及其相应治疗情况。
Cosmic电子病历是一个包含延雪平地区所有居民医疗信息的综合数据库。为进行一项基于人群的回顾性横断面研究，通过电子病历使用ICD - 10编码识别出2008年4月9日至2016年7月1日期间所有被诊断为银屑病的个体。分析了合并症数据以及针对这些合并症所开处方药的配药情况。
在研究期间，1.7%的人口（4587人）被诊断为银屑病，其中74.3%的病例被归类为轻度至中度银屑病，25.7%为重度。其余268949人未被诊断为银屑病。研究表明，银屑病患者发生所检查的大多数合并症的几率更高。除银屑病关节炎外的关节炎是银屑病患者中最常见的合并症诊断（调整后比值比7.2，95%置信区间6.4 - 8.2，p < 0.001），其次是肥胖（比值比2.4，95%置信区间1.9 - 3.1，p < 0.001）。除关节炎和戒烟治疗外，银屑病患者与非银屑病患者在合并症药物处方方面无显著差异。
与普通人群相比，银屑病患者更容易出现多种合并症，尤其是重度银屑病患者。除关节炎外，没有证据表明银屑病患者的合并症治疗不足。
