Laboratório de Bioquímica de Artrópodes Hematófagos, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Laboratório de Bioquímica de Artrópodes Hematófagos, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, RJ, Brazil; Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, RJ, Brazil.
Insect Biochem Mol Biol. 2022 Jul;146:103776. doi: 10.1016/j.ibmb.2022.103776. Epub 2022 May 6.
Wolbachia pipientis is a maternally transmitted bacterium that mostly colonizes arthropods, including the mosquito Aedes fluviatilis, potentially affecting different aspects of host physiology. This intracellular bacterium prefers gonadal tissue cells, interfering with the reproductive cycle of insects, arachnids, crustaceans, and nematodes. Wolbachia's ability to modulate the host's reproduction is related to its success in prevalence and frequency. Infecting oocytes is essential for vertical propagation, ensuring its presence in the germline. The mosquito Ae. fluviatilis is a natural host for this bacterium and therefore represents an excellent experimental model in the effort to understand host-symbiont interactions and the mutual metabolic regulation. The aim of this study was to comparatively describe metabolic changes in naturally Wolbachia-infected and uninfected ovaries of Ae. fluviatilis during the vitellogenic period of oogenesis, thus increasing the knowledge about Wolbachia parasitic/symbiotic mechanisms.
沃尔巴克氏体（Wolbachia pipientis）是一种通过母系遗传的细菌，主要寄生于节肢动物，包括蚊子 Aedes fluviatilis，可能会影响宿主生理的不同方面。这种细胞内细菌偏爱生殖组织细胞，干扰昆虫、蛛形纲动物、甲壳类动物和线虫的生殖周期。沃尔巴克氏体调节宿主生殖的能力与其在流行和频率方面的成功有关。感染卵母细胞对于垂直传播至关重要，确保其存在于生殖系中。蚊子 Ae. fluviatilis 是这种细菌的天然宿主，因此它是研究宿主-共生体相互作用和相互代谢调节的理想实验模型。本研究旨在比较描述在 Ae. fluviatilis 的卵发生期，自然感染和未感染沃尔巴克氏体的卵巢中的代谢变化，从而增加对沃尔巴克氏体寄生/共生机制的了解。
