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主要心血管危险因素在退休与心血管疾病关系中的修饰作用:SHARE 葡萄牙的研究结果。

The modifying role of major cardiovascular risk factors in the association between retirement and cardiovascular disease: Results from SHARE Portugal.

机构信息

Department of Epidemiology, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal.

Public Health Research Center, National School of Public Health, NOVA University of Lisbon, Lisbon, Portugal.

出版信息

Work. 2022;72(2):577-586. doi: 10.3233/WOR-205224.

Abstract

BACKGROUND

Despite the actual demographic trends and the global burden of cardiovascular diseases, there is little knowledge concerning the effects of retirement on this health outcome.

OBJECTIVE

We aimed to quantify the associations between retirement, and retirement age, with cardiovascular disease (heart disease and stroke) in the Portuguese population.

METHODS

We used data from the first Portuguese wave of the Survey of Health Ageing and Retirement in Europe. Logistic regression was applied to quantify the associations. The major risk factors for cardiovascular diseases and several features of retirement were considered as possible confounders or effect modifiers. Analysis was restricted to retirees in retirement process (retired for 5 years or less) and not retired because of illness.

RESULTS

An opposite direction of the association between retirement and heart disease was observed according to hypertension status, although not significant. Early retirement increased the odds of having a stroke, merely in individuals without heart disease (OR = 8.87; 95% CI 1.63-48.26). On the contrary, in individuals with heart disease, decreased the odds of having a stroke (OR = 0.08; 95% CI 0.01-0.68).

CONCLUSIONS

Our findings suggest that retirement and retirement age may be beneficial or harmful, respectively, in the presence or absence of major risk factors for heart disease and stroke. We suggest that work-related stress affecting differently workers with and without these risk factors may eventually explain these findings.

摘要

背景

尽管存在实际的人口趋势和全球心血管疾病负担,但对于退休对这一健康结果的影响知之甚少。

目的

我们旨在量化葡萄牙人口中退休和退休年龄与心血管疾病(心脏病和中风)之间的关联。

方法

我们使用了来自欧洲健康老龄化和退休调查的葡萄牙第一波数据。应用逻辑回归来量化关联。将心血管疾病的主要危险因素和退休的几个特征作为可能的混杂因素或效应修饰剂。分析仅限于处于退休过程中的退休人员(退休 5 年或以下)和因病未退休的人员。

结果

根据高血压状况,观察到退休与心脏病之间呈相反方向的关联,但无统计学意义。提前退休增加了没有心脏病的个体发生中风的几率(OR=8.87;95%CI 1.63-48.26)。相反,在患有心脏病的个体中,中风的几率降低(OR=0.08;95%CI 0.01-0.68)。

结论

我们的研究结果表明,退休和退休年龄可能分别对心脏病和中风的主要危险因素的存在或不存在有益或有害。我们认为,工作相关压力可能会对患有和不患有这些风险因素的工人产生不同的影响,这可能最终解释了这些发现。

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