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心房起搏抑制危重症患者室性心律失常:一例报告

Atrial pacing to suppress ventricular arrhythmias in the critically ill patients: a case report.

作者信息

Riad Omar, Russell Clare, Garfield Ben, Behar Jonathan M

机构信息

Cardiology Department, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

Department of Adult Intensive Care, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

出版信息

Eur Heart J Case Rep. 2022 Apr 16;6(5):ytac163. doi: 10.1093/ehjcr/ytac163. eCollection 2022 May.

Abstract

BACKGROUND

Atrial and ventricular arrhythmias are common in the critically ill due to a variety of factors including sepsis, myocardial ischaemia, renal dysfunction, and electrolyte disturbances. Anti-arrhythmic medications can be useful to control arrhythmias but can result in bradycardia and haemodynamic compromise. A paced atrial rhythm alongside normal atrioventricular conduction can be helpful to treat bradycardia, prevent arrhythmias, and support cardiac output.

CASE SUMMARY

A 55-year-old gentleman with pseudomonas pneumonia, respiratory failure necessitating mechanical haemodynamic support, and subsequent coronary ischaemia presented to the intensive care unit. Paroxysms of atrial fibrillation and ventricular arrhythmias caused haemodynamic embarrassment and presented an ongoing clinical challenge as anti-arrhythmic medications resulted in bradycardia and Torsade de Pointes. Atrial pacing mediated intrinsic conduction via the His-Purkinje system inhibited ventricular ectopy and further arrhythmia breaking the tachycardia-bradycardia cycle; this stabilized the patient, facilitated ongoing intensive therapy unit care and promoted recovery.

CONCLUSION

Atrial pacing mediated intrinsic conduction via the His-Purkinje system is an effective approach to suppress ventricular ectopy and sustained arrhythmias whilst protecting the patient from haemodynamically compromising bradycardia.

摘要

背景

由于多种因素,包括脓毒症、心肌缺血、肾功能不全和电解质紊乱,房性和室性心律失常在危重症患者中很常见。抗心律失常药物有助于控制心律失常,但可能导致心动过缓和血流动力学损害。伴有正常房室传导的心房起搏节律有助于治疗心动过缓、预防心律失常并支持心输出量。

病例摘要

一名55岁男性因假单胞菌肺炎、呼吸衰竭需要机械血流动力学支持以及随后出现冠状动脉缺血而入住重症监护病房。房颤和室性心律失常发作导致血流动力学窘迫,由于抗心律失常药物导致心动过缓和尖端扭转型室速,这带来了持续的临床挑战。心房起搏通过希氏-浦肯野系统介导固有传导,抑制室性早搏和进一步的心律失常,打破心动过速-心动过缓循环;这使患者病情稳定,便于在重症监护病房持续治疗并促进康复。

结论

心房起搏通过希氏-浦肯野系统介导固有传导是一种有效的方法,可抑制室性早搏和持续性心律失常,同时保护患者免受血流动力学损害的心动过缓影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3b3/9071316/d78c9e927a1d/ytac163f1.jpg

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