Molecular identification of species isolated from candiduria and its risk factors in neonates and children.

BACKGROUND AND PURPOSE

The present study was performed to raise attention on the frequency of spp. and evaluation of risk factors of candiduria in neonates and children.

MATERIALS AND METHODS

In total, 60 urine samples were collected from the suspected neonates and children. Identification of at species level was performed using the polymerase chain reaction-restriction fragment length polymorphism approach.

RESULTS

The restriction fragment length polymorphism fingerprint analysis revealed that (n=17; 28.33 %) is the most prevalent isolated species followed by (n=9; 15%), (n=4; 9.52%), and (n=2; 4.76%). All of the and complex strains were identified as with gene primers and using the restriction enzyme activity, respectively. In this study, none of the mentioned factors was the cause of infection, but they could be considered risk factors. The mean hospital stay was 21 days (range: 7-21 days). More than 90% of the patients had a urinary catheter, and about 26% of them received antibiotics. Regarding the risk factors, there was no significant difference between the two groups of candidiasis in terms of and non-albicans (<0.01).

CONCLUSION

Candiduria has always been a challenging issue, especially in children admitted to hospitals. Outcome of candiduria in patients with generally healthy is little.