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心胸外科医生的核医学心脏病学

Nuclear cardiology for a cardiothoracic surgeon.

作者信息

Mishra Anand Kumar, Singh Harpreet, Bansal Vidur, Raja Javid, Sood Ashwani

机构信息

Department of Cardiothoracic and Vascular Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012 India.

Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Thorac Cardiovasc Surg. 2022 May;38(3):268-282. doi: 10.1007/s12055-021-01311-0. Epub 2022 Mar 1.

Abstract

Cardiac surgeons are commonly faced with issues regarding the balance between the potential risk and the potential benefit of a surgical procedure. Nuclear cardiology procedures such as single-photon emission computed tomography and positron emission tomography provide the surgeon with objective information that augments standard clinical and angiographic assessments related to the diagnosis, prognosis, and potential benefit from any intervention. Myocardial perfusion is imaged with the use of radiopharmaceuticals that accumulate rapidly in the myocardium in proportion to the myocardial blood flow. Radionuclide lung imaging most commonly involves the demonstration of pulmonary perfusion using technetium-99 m macro aggregate albumin (Tc-99 m MAA), as well as the assessment of ventilation using inspired inert gas, usually xenon, or Tc-99 m-labelled aerosols. Nuclear cardiology is extensively used as a part of the work-up of ischemic heart disease and cardiac failure in deciding the optimal therapeutic strategy with its ability to predict the severity of the disease. It has also proved extremely useful in the management of congenital heart disease and the diagnosis of pulmonary embolism, among many other applications. Myocardial perfusion imaging is a basic adjunct to the noninvasive assessment of patients with stable angina, baseline electrocardiogram (ECG) abnormalities, post-revascularisation assessment, and heart failure. This review article covers a summary of basic concepts of nuclear cardiology about what a cardiac surgeon should be aware of. To many, it is just a perfusion test, but the versatility, reliability, and future of the technology are without a doubt.

摘要

心脏外科医生通常面临手术潜在风险与潜在益处之间平衡的问题。核心脏病学检查,如单光子发射计算机断层扫描和正电子发射断层扫描,为外科医生提供客观信息,增强了与诊断、预后以及任何干预措施潜在益处相关的标准临床和血管造影评估。心肌灌注通过使用与心肌血流成比例快速积聚在心肌中的放射性药物进行成像。放射性核素肺成像最常见的是使用锝-99m大聚合白蛋白(Tc-99m MAA)显示肺灌注,以及使用吸入的惰性气体(通常是氙气)或Tc-99m标记的气雾剂评估通气。核心脏病学因其预测疾病严重程度的能力,被广泛用作缺血性心脏病和心力衰竭检查工作的一部分,以确定最佳治疗策略。在先天性心脏病的管理和肺栓塞的诊断等许多其他应用中,它也已证明非常有用。心肌灌注成像对于稳定型心绞痛、基线心电图(ECG)异常、血管重建术后评估和心力衰竭患者的无创评估是一种基本辅助手段。这篇综述文章总结了心脏外科医生应了解的核心脏病学基本概念。对许多人来说,它只是一项灌注检查,但这项技术的多功能性、可靠性和未来发展无疑是值得关注的。

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