Milton S. Hershey Medical Center, Department of Radiology, Section of Nuclear Medicine, Pennsylvania State University, Hershey, PA.
Milton S. Hershey Medical Center, Department of Radiology, Section of Nuclear Medicine, Pennsylvania State University, Hershey, PA.
Semin Nucl Med. 2017 Nov;47(6):671-679. doi: 10.1053/j.semnuclmed.2017.08.001. Epub 2017 Aug 23.
Ventilation-perfusion scintigraphy (VPS) depicts the two main physiological processes that are fundamental to oxygen-dependent life. The test has affirmed its critical place in the evaluation of patients with lung cancer preparing for lung resection. The results of the study can differentiate patients who are very likely to survive surgery and the subsequent pulmonary function loss from those who are not. This review presents validated and evolving testing techniques for this critical indication. VPS has long been an integral part of the preoperative evaluation of lung transplant candidates, guiding the single lung grafts to the side with the worst function. New applications are emerging in the rapidly developing surgical and interventional management of severe chronic obstructive lung diseases. Enhanced by the advancements in hybrid imaging and computer processing, the VPS examination continues to be reinvented and updated to keep pace with the needs of modern medicine.
通气灌注闪烁显像（VPS）描绘了对依赖氧气的生命至关重要的两个主要生理过程。该检查已证实其在准备进行肺癌肺切除手术的患者评估中的重要地位。研究结果可以区分出术后很可能存活且肺功能丧失的患者与不能存活的患者。本综述介绍了针对这一关键适应证的经过验证和不断发展的检测技术。VPS 一直是肺移植候选者术前评估的一个组成部分，指导单肺移植到功能最差的一侧。在严重慢性阻塞性肺疾病的快速发展的外科和介入管理中，新的应用正在出现。得益于混合成像和计算机处理的进步，VPS 检查不断被重新设计和更新，以满足现代医学的需求。
