Kawakado Keita, Hotta Takamasa, Sakamoto Jin, Horie Mika, Kobayashi Misato, Okuno Takae, Amano Yoshihiro, Hamaguchi Megumi, Tsubata Yukari, Kurimoto Noriaki, Isobe Takeshi
Department of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine, Izumo, Japan.
Department of Respiratory Surgery, Shimane Prefectural Central Hospital, Izumo, Japan.
Case Rep Oncol. 2022 Mar 30;15(1):356-361. doi: 10.1159/000523941. eCollection 2022 Jan-Apr.
The patient, a 62-year-old woman, complained chiefly of cough. We planned chemoradiotherapy for squamous nonsmall cell lung cancer. A single dose of 2-Gy irradiation and no anticancer agent administration exacerbated the airway stenosis with severe respiratory failure. Urgent tracheal intubation was performed, and a tracheal stent was implanted under extracorporeal membrane oxygenation (ECMO). Because her performance status (PS) worsened from 1 to 2, we administered radiotherapy. The tumor size decreased. There was no recurrence for the next 3 months, and her PS improved to 1. Emergency tracheal intubation and tracheal stent placement under ECMO can be effective for exacerbated airway obstruction after radiotherapy.
该患者为一名62岁女性，主要症状为咳嗽。我们计划对其鳞状非小细胞肺癌进行放化疗。单次2Gy照射且未给予抗癌药物治疗加重了气道狭窄并导致严重呼吸衰竭。紧急进行了气管插管，并在体外膜肺氧合（ECMO）支持下植入了气管支架。由于其体能状态（PS）从1级恶化为2级，我们给予了放射治疗。肿瘤大小缩小。接下来的3个月没有复发，其PS改善至1级。在ECMO支持下进行紧急气管插管和气管支架置入对放疗后加重的气道阻塞可能有效。
