Song Mi, Chen Baihua
Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha, China.
Hunan Clinical Research Center of Ophthalmic Disease, Changsha, China.
Front Nutr. 2022 Apr 21;9:812476. doi: 10.3389/fnut.2022.812476. eCollection 2022.
Age-related macular degeneration (AMD) is the main irreversible blindness disease worldwide. The current study aimed to investigate whether the consumption of 100% fruit juice increases the risk of age-related macular degeneration and find approaches to prevent and reduce the development of age-related macular degeneration from the aspect of dietary habits. A cross-sectional clinical study design was adopted. We screened participants from the 2005 to 2006 NHANES database. The logistic regression model was used to evaluate the relationship between 100% fruit juice consumption and advanced AMD and to adjust variables such as demographics, general health status, body mass index (BMI), health-related behaviors, systemic complications, and ophthalmic complications. The results show that 100% fruit juice consumption did not affect early AMD and any AMD. High consumers of 100% fruit juice are more likely to develop advanced age-related macular degeneration than those who never drink 100% fruit juice.
年龄相关性黄斑变性（AMD）是全球主要的不可逆致盲疾病。当前研究旨在调查饮用100%果汁是否会增加年龄相关性黄斑变性的风险，并从饮食习惯方面寻找预防和减少年龄相关性黄斑变性发展的方法。采用横断面临床研究设计。我们从2005年至2006年的美国国家健康与营养检查调查（NHANES）数据库中筛选参与者。使用逻辑回归模型评估饮用100%果汁与晚期AMD之间的关系，并对人口统计学、总体健康状况、体重指数（BMI）、健康相关行为、全身并发症和眼科并发症等变量进行调整。结果显示，饮用100%果汁不会影响早期AMD和任何AMD。与从不饮用100%果汁的人相比，大量饮用100%果汁的人更有可能患上晚期年龄相关性黄斑变性。
