Pliakou Evangelia, Lampropoulou Dimitra-Ioanna, Soupos Nikolaos, Aravantinos Gerasimos
Second Department of Medical Oncology, General Oncology Hospital of Kifissia "Agioi Anargiroi", Athens, Nea Kifissia 14564, Greece.
Case Rep Gastrointest Med. 2022 Apr 28;2022:7535036. doi: 10.1155/2022/7535036. eCollection 2022.
Multiple primary cancer (MPC) is defined as more than one primary tumour diagnosed at the same patient, either simultaneously or sequentially. Its incidence is low and varies in reporting among medical centers. Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL) while gastric cancer (GC) is the fifth most frequently diagnosed malignancy. The aim of this article is to present a rare case of a female patient who was diagnosed with two synchronous malignancies, an adenocarcinoma of the stomach (SRCC) and an aggressive extranodal NH lymphoma (DLBCL) within 2 months. Given the fact that there is an expanding availability of more sensitive diagnostic and screening methods, we aim to increase surveillance amongst medical doctors and provide valuable information for further systematic analysis and identification of such rare cases of concurrent malignancies.
多原发性癌(MPC)被定义为在同一患者身上诊断出的不止一种原发性肿瘤,可同时或先后出现。其发病率较低,不同医疗中心的报告存在差异。弥漫性大B细胞淋巴瘤(DLBCL)是非霍奇金淋巴瘤(NHL)最常见的亚型,而胃癌(GC)是第五大最常诊断出的恶性肿瘤。本文的目的是介绍一例罕见病例,一名女性患者在2个月内被诊断出患有两种同步恶性肿瘤,即胃腺癌(SRCC)和侵袭性结外NHL淋巴瘤(DLBCL)。鉴于更敏感的诊断和筛查方法的可用性不断增加,我们旨在提高医生的监测意识,并为进一步系统分析和识别此类罕见的并发恶性肿瘤病例提供有价值的信息。